Zinc Finger Protein 496 (ZNF496) (N-Term) antibody

Details for Product No. ABIN183828
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Synonyms NIZP1, ZFP496, ZKSCAN17, ZSCAN49, Zkscan17, Znf496, ZNF496
(3), (3), (3), (2), (1)
Mouse (Murine), Dog (Canine), Cow (Bovine), Human
(17), (5), (2), (2)
(11), (7)
Western Blotting (WB)
(17), (6), (6), (2), (2), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN183828
Quantity 100 µg
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Immunogen Synthetic peptide directed towards the N terminal of human ZNF496
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Pig : 100 %, Sheep : 100 %, Guinea pig : 90 %
Characteristics This is a rabbit polyclonal antibody against ZNF496. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name ZNF496
Background ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
Molecular Weight 67 kDa
Gene ID 84838
NCBI Accession NM_032752, NP_116141
UniProt Q96IT1
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 587 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Zinc Finger Protein 496 (ZNF496) (N-Term) antibody WB Suggested Anti-ZNF496 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
Background publications Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Hosts (11), (7)
Reactivities (17), (5), (2), (2)
Applications (17), (6), (6), (2), (2), (2), (1)
Epitopes (3), (3), (3), (2), (1)
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