Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) (N-Term) antibody

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Antigen
Epitope
N-Term
(23), (15), (5), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human
(41), (9), (7), (3), (3)
Host
Rabbit
(36), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(37), (22), (7), (3), (3)
Pubmed 4 references available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human HNRPLL
Sequence RLKTEEGEID YSAEEGENRR EATPRGGGDG GGGGRSFSQP EAGGSHHKVS
Predicted Reactivity Bovine : 100 %, Human : 100 %, Rabbit : 100 %, Guinea pig : 90 %
Characteristics This is a rabbit polyclonal antibody against HNRPLL. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name HNRPLL (HNRPLL Antibody Abstract)
Background HNRPLL contains 3 RRM (RNA recognition motif) domains and may bind RNA and plays a role in mRNA processing.
Molecular Weight 60 kDa
Gene ID 92906
NCBI Accession NP_612403, NM_138394
UniProt Q8WVV9
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 542 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) (N-Term) antibody (ABIN184075) WB Suggested Anti-HNRPLL Antibody Titration: 1.25ug/ml
Positive Control:...
Immunohistochemistry (IHC) image for anti-Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) (N-Term) antibody (ABIN184075) anti-Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) (N-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) (N-Term) antibody (ABIN184075) anti-Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) (N-Term) antibody (Image 3)
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) (N-Term) antibody (ABIN184075) Host: Rabbit
Target Name: HNRPLL
Sample Tissue: HepG2Lane A: Primary A...
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) (N-Term) antibody (ABIN184075) WB Suggested Anti-HNRPLL
Antibody Titration: 1.25 µg/mL
Positive Contro...
Product cited in: Heyd, Lynch: "Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing." in: Molecular cell, Vol. 40, Issue 1, pp. 126-37, 2010 (PubMed).

Rajan, Dalgliesh, Bourgeois et al.: "Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies." in: BMC cell biology, Vol. 10, pp. 82, 2009 (PubMed).

Yu, Hai, Liu et al.: "The heterogeneous nuclear ribonucleoprotein L is an essential component in the Ca2+/calmodulin-dependent protein kinase IV-regulated alternative splicing through cytidine-adenosine repeats." in: The Journal of biological chemistry, Vol. 284, Issue 3, pp. 1505-13, 2009 (PubMed).

Background publications Shur, Ben-Avraham, Benayahu: "Alternatively spliced isoforms of a novel stromal RNA regulating factor." in: Gene, Vol. 334, pp. 113-21, 2004 (PubMed).

Catalog No. ABIN184075
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