Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) (N-Term) antibody

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Antigen
Epitope
N-Term
(18), (16), (1), (1), (1)
Reactivity
Human
(25), (3), (3)
Host
Rabbit
(24), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (1)
Application
Western Blotting (WB)
(22), (15), (3), (2), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human CHRNA2
Sequence TKLSLWWLLL TPAGGEEAKR PPPRAPGDPL SSPSPTALPQ GGSHTETEDR
Predicted Reactivity Human : 100 %  
Characteristics This is a rabbit polyclonal antibody against CHRNA2. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name CHRNA2 (CHRNA2 Antibody Abstract)
Background After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Molecular Weight 60 kDa
Gene ID 1135
NCBI Accession NM_000742, NP_000733
UniProt Q15822
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 529 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) (N-Term) antibody (ABIN184249) anti-Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) (N-Term) antibody
Background publications Elliott, Ellis, Berckhan et al.: "Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits." in: Journal of molecular neuroscience : MN, Vol. 7, Issue 3, pp. 217-28, 1997 (PubMed).

Catalog No. ABIN184249
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