Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) (N-Term) antibody

Details for Product No. ABIN184249
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Antigen
Synonyms ACHR, NACHRA2, Acra-2, Acra2, BC011490
Epitope
N-Term
(8), (8), (1)
Reactivity
Human
(10)
Host
Rabbit
(9), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(10), (8)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN184249
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Immunogen Synthetic peptide directed towards the N terminal of human CHRNA2
Sequence TKLSLWWLLL TPAGGEEAKR PPPRAPGDPL SSPSPTALPQ GGSHTETEDR
Predicted Reactivity Human : 100 %  
Characteristics This is a rabbit polyclonal antibody against CHRNA2. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name CHRNA2
Background After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Molecular Weight 60 kDa
Gene ID 1135
NCBI Accession NM_000742, NP_000733
UniProt Q15822
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 529 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) (N-Term) antibody anti-Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) (N-Term) antibody
Background publications Elliott, Ellis, Berckhan et al.: "Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits." in: Journal of molecular neuroscience : MN, Vol. 7, Issue 3, pp. 217-28, 1997 (PubMed).

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