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Details for Product No. ABIN184249

Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) (N-Term) antibody

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Antigen
Synonyms NACHRA2, Acra-2, Acra2, BC011490
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN184249
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-CHRNA2 antibody: synthetic peptide directed towards the N terminal of human CHRNA2
Sequence TKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQ GGSHTETEDR
Predicted Reactivity Human : 100%  
Characteristics This is a rabbit polyclonal antibody against CHRNA2. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Protein A purified
Alternative Name CHRNA2
Background After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Molecular Weight 60kDa
Gene ID 1135
NCBI Accession NP_000733, NM_000742
UniProt Q15822
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-CHRNA2 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Elliott, Ellis, Berckhan et al.: "Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits." in: Journal of molecular neuroscience : MN, Vol. 7, Issue 3, pp. 217-28, 1997 (PubMed).

Alternatives for antigen "Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2)", type "Antibodies"
Hosts (5), (1)
Reactivities (6)
Applications (6), (2)
Epitopes (4), (2), (2), (1)
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