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Filamin B, beta (FLNB) (Internal Region) antibody

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Synonyms ABP-278, ABP-280, AOI, FH1, FLN-B, FLN1L, LRS1, SCT, TABP, TAP, AL024016
Internal Region
(7), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
(54), (23), (21), (2), (2), (1), (1)
(48), (6), (1)
(5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
ELISA, Western Blotting (WB)
(27), (19), (14), (11), (10), (6), (4), (3), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
Shipping to United States ( )
Availability Available
Immunogen Peptide with sequence KITDDSRRCSQVK, from the internal region of the protein sequence according to NP_001448.2, NP_001157789.1, NP_001157790.1, NP_001157791.1.
Blocking Peptide Blocking peptide for this product available: ABIN370214
Specificity This antibody is expected to recognise all reported isoforms (NP_001448.2, NP_001157789.1, NP_001157790.1, NP_001157791.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name FLNB (FLNB Antibody Abstract)
Background Synonyms: FLNB, filamin B, beta (actin binding protein 278), ABP-278, AOI, DKFZp686A1668, DKFZp686O033, FH1, FLN1L, LRS1, SCT, TABP, TAP, filamin B, beta filamin, filamin 1 (actin-binding protein-280)-like, filamin B, beta (actin-binding protein-278)
Gene ID 2317, 286940, 306204
NCBI Accession NP_001157789, NP_001448, NP_001157790, NP_001157791
Research Area Signaling, Cytoskeleton, Microfilaments
Application Notes ELISA: antibody detection limit dilution 1:16000.
Western blot: Preliminary experiments in Human Brain, Mouse Brain and Rat Brain lysates gave no specific signal but low background (at antibody concentration up to 1 µg/mL).
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Background publications Takafuta, Wu, Murphy et al.: "Human beta-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein Ibalpha." in: The Journal of biological chemistry, Vol. 273, Issue 28, pp. 17531-8, 1998 (PubMed).

Catalog No. ABIN185734
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