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Filamin B, beta (FLNB) (Internal Region) antibody

Details for Product No. ABIN185734, Supplier: Login to see
Antigen
  • ABP-278
  • ABP-280
  • AOI
  • FH1
  • FLN-B
  • FLN1L
  • LRS1
  • SCT
  • TABP
  • TAP
  • AL024016
Epitope
Internal Region
7
4
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
50
23
21
2
2
1
1
Host
Goat
44
6
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
1
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
23
16
13
11
9
5
2
2
1
1
1
1
Supplier
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Immunogen Peptide with sequence KITDDSRRCSQVK, from the internal region of the protein sequence according to NP_001448.2, NP_001157789.1, NP_001157790.1, NP_001157791.1.
Blocking Peptide Blocking peptide for this product available: ABIN370214
Specificity This antibody is expected to recognise all reported isoforms (NP_001448.2, NP_001157789.1, NP_001157790.1, NP_001157791.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name FLNB (FLNB Antibody Abstract)
Background Synonyms: FLNB, filamin B, beta (actin binding protein 278), ABP-278, AOI, DKFZp686A1668, DKFZp686O033, FH1, FLN1L, LRS1, SCT, TABP, TAP, filamin B, beta filamin, filamin 1 (actin-binding protein-280)-like, filamin B, beta (actin-binding protein-278)
Gene ID 2317, 286940, 306204
NCBI Accession NP_001157789, NP_001448, NP_001157790, NP_001157791
Research Area Signaling, Cytoskeleton, Microfilaments
Pathways
Application Notes ELISA: antibody detection limit dilution 1:16000.
Western blot: Preliminary experiments in Human Brain, Mouse Brain and Rat Brain lysates gave no specific signal but low background (at antibody concentration up to 1 µg/mL).
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Background publications Takafuta, Wu, Murphy et al.: "Human beta-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein Ibalpha." in: The Journal of biological chemistry, Vol. 273, Issue 28, pp. 17531-8, 1998 (PubMed).