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TNFRSF1A antibody
TNFRSF1A
Reactivity: Human
FACS, IHC (fro), IA, Agon, CC
Host: Mouse
Monoclonal
MR1-2
unconjugated
Product Details anti-TNFRSF1A Antibody
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Target
See all TNFRSF1A Antibodies
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Reactivity
All reactivities for TNFRSF1A antibodies
Human
Host
All hosts for TNFRSF1A antibodies
Mouse
Clonality
All clonalities for TNFRSF1A antibodies
Monoclonal
Conjugate
All conjugates for TNFRSF1A antibodies
This TNFRSF1A antibody is un-conjugated
Application
All applications for TNFRSF1A antibodies
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA), Agonist (Agon), Cell Culture (CC)
Sterility
0.2 μm filtered
Clone
MR1-2
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Discover our top product TNFRSF1A Primary Antibody
Alternatives
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Application Details
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Application Notes
For immunohistology and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. Advised positive controls for frozen sections are human lymphnodes and for flow cytometry PHA activated T cells.
Restrictions
For Research Use only
Handling
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Buffer
PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Expiry Date
12 months
References for anti-TNFRSF1A antibody (ABIN2191868)
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Leeuwenberg, Dentener, Buurman : "Lipopolysaccharide LPS-mediated soluble TNF receptor release and TNF receptor expression by monocytes. Role of CD14, LPS binding protein, and bactericidal/permeability-increasing protein. " in: Journal of immunology (Baltimore, Md. : 1950) , Vol. 152 , Issue 10 , pp. 5070-6 , (1994 ) (PubMed ).
Target Details for TNFRSF1A
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Target
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Alternative Name
Cd120a, Tnf-R I (TNFRSF1A Products )
Synonyms
CD120a antibody, FPF antibody, MS5 antibody, TBP1 antibody, TNF-R antibody, TNF-R-I antibody, TNF-R55 antibody, TNFAR antibody, TNFR1 antibody, TNFR1-d2 antibody, TNFR55 antibody, TNFR60 antibody, p55 antibody, p55-R antibody, p60 antibody, TNF-R1 antibody, TNF-alphaR1 antibody, TNFRI antibody, TNFRp55 antibody, TNFalpha-R1 antibody, Tnfr-2 antibody, Tnfr1 antibody, fpf antibody, tbp1 antibody, p55-r antibody, tnf-r antibody, tnfar antibody, tnfr1 antibody, cd120a antibody, tnfr55 antibody, tnfr60 antibody, xtnfr1 antibody, wu:fj65b10 antibody, zgc:85914 antibody, TNFR I antibody, TNFRSF1A antibody, TNFA antibody, cTNF antibody, TNF receptor superfamily member 1A antibody, tumor necrosis factor receptor superfamily, member 1a antibody, TNF receptor superfamily member 1A S homeolog antibody, tumor necrosis factor antibody, TNFRSF1A antibody, Tnfrsf1a antibody, tnfrsf1a.S antibody, tnfrsf1a antibody, TNF antibody
Background
The antibody MR1-2 reacts with the extra-cellular part of the TNF-R I. It also reacts with the soluble receptor. TNF-R I is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha: Induction of cytotoxicity and other functions are mediated largely via TNF-R I. The antibody cross reacts with rhesus and cynomolgus natural TNF-R I.
Pathways
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , Hepatitis C , Ubiquitin Proteasome Pathway
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