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Arylsulfatase A antibody (ARSA) (Internal Region)

Details for Product anti-ARSA Antibody No. ABIN238536, Supplier: Log in to see
Antigen
  • ARSA
  • zgc:101575
  • arsa
  • AS-A
  • ASA
  • AW212749
  • As-2
  • As2
  • TISP73
  • MLD
  • mld
Epitope
Internal Region
34
13
10
9
7
4
4
3
3
2
2
2
1
1
1
1
1
Reactivity
Mouse (Murine)
105
45
37
3
3
2
1
1
1
Host
Goat
76
21
14
Clonality
Polyclonal
Conjugate
This Arylsulfatase A antibody is un-conjugated
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
85
48
26
12
8
4
1
1
1
Supplier
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Immunogen Peptide with sequence C-YDLSKDPGENYN, from the internal region of the protein sequence according to NP_000478.2.
Blocking Peptide Blocking peptide for this product available: ABIN370036
Cross-Reactivity Human, Rat (Rattus)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Arylsulfatase A (ARSA Antibody Abstract)
Background Synonyms: ARSA, arylsulfatase A, MLD, cerebroside-sulfatase, cerebroside 3-sulfatase
Gene ID 410, 11883, 315222
NCBI Accession NP_000478
Pathways
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 55 kDa band observed in Mouse Testis lysates (calculated MW of 53.6 kDa according to human NP_000478.2 and 53.7 kDa according to Mouse NP_033843.2). Recommended concentration: 0.5-1.5 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-Arylsulfatase A antibody (ARSA) (Internal Region) (ABIN238536) ABIN238536 (0.5µg/ml) staining of Mouse Testis lysate (35µg protein in RIPA buffer). ...
Product cited in: Kanbe, Kamijo, Nakajima et al.: "Chronic ethanol consumption decreases serum sulfatide levels by suppressing hepatic cerebroside sulfotransferase expression in mice." in: Archives of toxicology, Vol. 88, Issue 2, pp. 367-79, 2014 (PubMed).

Kimura, Nakajima, Kamijo et al.: "Hepatic Cerebroside Sulfotransferase Is Induced by PPAR? Activation in Mice." in: PPAR research, Vol. 2012, pp. 174932, 2012 (PubMed).

Kiebish, Young, Lehman et al.: "Chronic caloric restriction attenuates a loss of sulfatide content in PGC-1?-/- mouse cortex: a potential lipidomic role of PGC-1? in neurodegeneration." in: Journal of lipid research, Vol. 53, Issue 2, pp. 273-81, 2012 (PubMed).

Zhang, Nakajima, Kamijo et al.: "Acute kidney injury induced by protein-overload nephropathy down-regulates gene expression of hepatic cerebroside sulfotransferase in mice, resulting in reduction of liver and serum sulfatides." in: Biochemical and biophysical research communications, Vol. 390, Issue 4, pp. 1382-8, 2009 (PubMed).

Background publications Sevin, Benraiss, Van Dam et al.: "Intracerebral adeno-associated virus-mediated gene transfer in rapidly progressive forms of metachromatic leukodystrophy." in: Human molecular genetics, Vol. 15, Issue 1, pp. 53-64, 2005 (PubMed).