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Details for Product No. ABIN238536

Arylsulfatase A (ARSA) (Internal Region) antibody

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Antigen
Synonyms MLD, AS-A, ASA, AW212749, As-2, As2, TISP73, ARSA, arsa, mld, zgc:101575
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Mouse (Murine)
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN238536
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-YDLSKDPGENYN, from the internal region of the protein sequence according to NP_000478.2.
Cross-Reactivity Human, Rat (Rattus)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Arylsulfatase A
Background Synonyms: ARSA, arylsulfatase A, MLD, cerebroside-sulfatase, cerebroside 3-sulfatase
Gene ID 410, 11883, 315222
NCBI Accession NP_000478.2
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 55 kDa band observed in Mouse Testis lysates (calculated MW of 53.6 kDa according to human NP_000478.2 and 53.7 kDa according to Mouse NP_033843.2). Recommended concentration: 0.5-1.5 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Product cited in: Zhang, Nakajima, Kamijo et al.: "Acute kidney injury induced by protein-overload nephropathy down-regulates gene expression of hepatic cerebroside sulfotransferase in mice, resulting in reduction of liver and serum sulfatides." in: Biochemical and biophysical research communications, Vol. 390, Issue 4, pp. 1382-8, 2009 (PubMed).

Kiebish, Young, Lehman et al.: "Chronic caloric restriction attenuates a loss of sulfatide content in PGC-1α-/- mouse cortex: a potential lipidomic role of PGC-1α in neurodegeneration." in: Journal of lipid research, Vol. 53, Issue 2, pp. 273-81, 2012 (PubMed).

Kimura, Nakajima, Kamijo et al.: "Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in Mice." in: PPAR research, Vol. 2012, pp. 174932, 2012 (PubMed).

Sevin, Benraiss, Van Dam et al.: "Intracerebral adeno-associated virus-mediated gene transfer in rapidly progressive forms of metachromatic leukodystrophy." in: Human molecular genetics, Vol. 15, Issue 1, pp. 53-64, 2005 (PubMed).

Alternatives for antigen "Arylsulfatase A (ARSA)", type "Antibodies"
Hosts (46), (7), (6)
Reactivities (55), (37), (36), (14), (14), (14), (1)
Applications (39), (19), (18), (11), (7), (2), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (8), (4), (4), (2), (2), (2), (1), (1)
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