Interleukin 17a antibody (PE)

Catalog No. ABIN2568240

Product Details anti-Interleukin 17a Antibody (PE)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse, Rat

Host: Rat

Clonality: Monoclonal

Conjugate: This Interleukin 17a antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine.

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone: 17B7

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL-17A (IL17A Products)

Background: The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells.

Gene ID: 16171, 301289

UniProt: Q62386, Q61453