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Details for Product No. ABIN310738

Protein O-Fucosyltransferase 2 (POFUT2) (N-Term) antibody

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Synonyms FUT13, C21orf80, 2310011G23Rik, AI256847, BC003494, fc46a11, wu:fc46a11, zgc:194822
»Alternatives N-Term
»Alternatives Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Cow (Bovine), Human, Chicken
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN310738
Quantity 50 µg
289.00 $   Plus shipping costs $45.00
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Immunogen The immunogen for anti-POFUT2 antibody: synthetic peptide directed towards the N terminal of human POFUT2
Predicted Reactivity Bovine : 100%, Chicken : 100%, Guinea pig : 100%, Horse : 100%, Mouse : 100%, Rat : 100%, Zebrafish : 100%
Characteristics This is a rabbit polyclonal antibody against POFUT2. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name POFUT2
Background POFUT2 catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF, MIM 131530)-like repeats or thrombospondin (THBS, see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).
Molecular Weight 50kDa
Gene ID 23275
NCBI Accession NP_598368, NM_133635
UniProt Q9Y2G5
Research Area Signaling, Metabolism, Organelles
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-POFUT2 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Product cited in: Luo, Koles, Vorndam et al.: "Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9393-9, 2006 (PubMed).

Background publications Luo, Nita-Lazar, Haltiwanger: "Two distinct pathways for O-fucosylation of epidermal growth factor-like or thrombospondin type 1 repeats." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9385-92, 2006 (PubMed).

Alternatives for antigen "Protein O-Fucosyltransferase 2 (POFUT2)", type "Antibodies"
Hosts (17), (4)
Reactivities (18), (6), (2)
Applications (15), (10), (9), (3), (3), (1)
Epitopes (3), (2), (2), (1), (1), (1), (1)