Transglutaminase 5 (TGM5) (C-Term) antibody

Details for Product No. ABIN311154
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Antigen
Synonyms TGM5, TGASE5, TGASEX, TGMX, TGX, 2310007C07Rik, TGx
Epitope
C-Term
(16), (7), (2), (1)
Reactivity
Mouse (Murine), Dog (Canine), Cow (Bovine), Human
(31), (6), (6)
Host
Rabbit
(31), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(32), (24), (9), (3), (3), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN311154
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human TGM5
Sequence VLKPQHQASI ILETVPFKSG QRQIQANMRS NKFKDIKGYR NVYVDFAL
Predicted Reactivity Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Bovine : 90 %, Horse : 90 %, Mouse : 80 %, Rat : 80 %, Rabbit : 80 %, Pig : 70 %
Characteristics This is a rabbit polyclonal antibody against TGM5. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TGM5
Background TGM5 belongs to the transglutaminase superfamily, transglutaminase family. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It contributes to the formation of the cornified cell envelope of keratinocytes. Defects in TGM5 are a cause of peeling skin syndrome acral type (APSS).
Molecular Weight 81 kDa
Gene ID 9333
NCBI Accession NM_201631, NP_963925
UniProt O43548
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 720 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Transglutaminase 5 (TGM5) (C-Term) antibody WB Suggested Anti-TGM5 Antibody Titration: 0.2-1 ug/ml
Positive Control: Hela cell lysate
Background publications Cassidy, van Steensel, Steijlen et al.: "A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome." in: American journal of human genetics, Vol. 77, Issue 6, pp. 909-17, 2005 (PubMed).

Validation Images
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