Prostate Tumor Overexpressed 1 (PTOV1) (N-Term) antibody

Details for Product No. ABIN311328
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Antigen
Synonyms 1110030G05Rik, AU041779, Gcap3, ACID2, PTOV-1
Epitope
N-Term
(9), (8), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(23), (14), (13), (1)
Host
Rabbit
(23)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(14), (10), (6), (6), (5), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN311328
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human PTOV1
Sequence DSTAKLKRTL PCQAYVNQGE NLETDQWPQK LIMQLIPQQL LTTLGPLFRN
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %
Characteristics This is a rabbit polyclonal antibody against PTOV1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PTOV1
Background PTOV1 belongs to the Mediator complex subunit 25 family, PTOV1 subfamily. It may activate transcription and is required for nuclear translocation of FLOT1. PTOV1 promotes cell proliferation.
Molecular Weight 47 kDa
Gene ID 53635
NCBI Accession NM_017432, NP_059128
UniProt Q86YD1
Research Area Cancer, Cell Cycle, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 416 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Prostate Tumor Overexpressed 1 (PTOV1) (N-Term) antibody WB Suggested Anti-PTOV1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
Background publications Santamaría, Castellanos, Gómez et al.: "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1900-11, 2005 (PubMed).

Validation Images
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