Dynein, Cytoplasmic 1, Intermediate Chain 1 (DYNC1I1) (N-Term) antibody

Details for Product No. ABIN311487
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Antigen
Epitope
N-Term
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human, Chicken
Host
Rabbit
Clonality
Polyclonal
Application
Western Blotting (WB)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN311487
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Immunogen Synthetic peptide directed towards the N terminal of human DYNC1I1
Sequence IREEKKRKEE ERKKKEADMQ QKKEPVQDDS DLDRKRRETE ALLQSIGISP
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rat : 90 %, Chicken : 80 %
Characteristics This is a rabbit polyclonal antibody against DYNC1I1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name DYNC1I1
Background DYNC1I1 belongs to the dynein intermediate chain family. It contains 7 WD repeats. The intermediate chains seem to help dynein bind to dynactin 150 kDa component. DYNC1I1 may play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Molecular Weight 73 kDa
Gene ID 1780
NCBI Accession NP_004402, NM_004411
UniProt O14576
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 645 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Dynein, Cytoplasmic 1, Intermediate Chain 1 (DYNC1I1) (N-Term) antibody WB Suggested Anti-DYNC1I1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human brain
Background publications Pfister, Fisher, Gibbons et al.: "Cytoplasmic dynein nomenclature." in: The Journal of cell biology, Vol. 171, Issue 3, pp. 411-3, 2005 (PubMed).

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