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Details for Product No. ABIN311506

Coatomer Protein Complex, Subunit beta 1 (COPB1) (Middle Region) antibody

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Antigen
Synonyms COPB, 2610019B04Rik, Rack2, id:ibd5034, wu:fc66c05, zgc:92482, Beta-COP, COPB1, DKFZp459K154
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Pig (Porcine), Xenopus laevis, Zebrafish (Danio rerio), Fruit Fly (Drosophila melanogaster), Human, Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN311506
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-COPB1 antibody: synthetic peptide directed towards the middle region of human COPB1
Sequence QLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQ LLVRTLHSCS
Predicted Reactivity Dog : 100%, Guinea pig : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rabbit : 100%, African clawed frog : 92%, Horse : 92%
Characteristics This is a rabbit polyclonal antibody against COPB1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name COPB1
Background The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Molecular Weight 107kDa
Gene ID 1315
NCBI Accession NP_057535, NM_016451
UniProt P53618
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-COPB1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Product cited in: Goryachev, Pokhilko: "Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes." in: PLoS computational biology, Vol. 2, Issue 12, pp. e172, 2007 (PubMed).

Alternatives for antigen "Coatomer Protein Complex, Subunit beta 1 (COPB1)", type "Antibodies"
Hosts (11), (7)
Reactivities (14), (5), (3), (2), (1), (1), (1), (1), (1)
Applications (15), (8), (8), (4), (2), (2), (1), (1)
Epitopes (3), (2), (2), (2), (1), (1), (1)
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