Zinc Finger, CCHC Domain Containing 12 (ZCCHC12) (N-Term) antibody

Details for Product No. ABIN311555
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Synonyms PNMA7A, SIZN, SIZN1, Sizn1, AV136720, 2810028A01Rik
(2), (2), (1), (1), (1), (1), (1)
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human
(8), (1), (1)
(10), (1)
Western Blotting (WB)
(9), (2), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN311555
Quantity 50 µg
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Immunogen Synthetic peptide directed towards the N terminal of human ZCCHC12
Predicted Reactivity Dog : 92 %, Guinea pig : 92 %, Horse : 92 %, Mouse : 92 %
Characteristics This is a rabbit polyclonal antibody against ZCCHC12. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ZCCHC12
Background ZCCHC12 contains 1 CCHC-type zinc finger. ZCCHC12 is the transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.
Molecular Weight 45 kDa
Gene ID 170261
NCBI Accession NM_173798, NP_776159
UniProt Q6PEW1
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 402 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Zinc Finger, CCHC Domain Containing 12 (ZCCHC12) (N-Term) antibody WB Suggested Anti-ZCCHC12 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Background publications Cho, Lim, Zand et al.: "Sizn1 is a novel protein that functions as a transcriptional coactivator of bone morphogenic protein signaling." in: Molecular and cellular biology, Vol. 28, Issue 5, pp. 1565-72, 2008 (PubMed).

Hosts (10), (1)
Reactivities (8), (1), (1)
Applications (9), (2), (2), (1)
Epitopes (2), (2), (1), (1), (1), (1), (1)
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