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BIN1 antibody (Bridging Integrator 1) (Internal Region)

Details for Product anti-BIN1 Antibody No. ABIN334360, Supplier: Login to see New
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Antigen
Synonyms bin1, MGC53185, amph2, amphl, sh3p9, MGC76187, cb57, zgc:86701, BIN1, AMPH2, AMPHL, SH3P9, ALP-1, Amphl, BRAMP-2
Epitope
Internal Region
(18), (11), (8), (7), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(84), (42), (26), (3), (2), (2), (1), (1), (1), (1)
Host
Goat
(42), (31), (14)
Clonality
Polyclonal
Conjugate
This BIN1 antibody is un-conjugated
(2), (2), (2), (2), (2), (2), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(75), (40), (29), (11), (9), (8), (7), (6), (3), (2), (2), (2), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Peptide with sequence C-SDNAPAKGNKSPS, from the internal region of the protein sequence according to NP_004296.1, NP_647593.1, NP_647594.1, NP_647595.1, NP_647596.1, NP_647597.1, NP_647598.1, NP_647599.1, NP_647600.1, NP_647601.1.
Blocking Peptide Blocking peptide for this product available: ABIN369855
Specificity This antibody is expected to recognise all ten reported isoforms (NP_647593.1, NP_647594.1, NP_647595.1, NP_647596.1, NP_647597.1, NP_647598.1, NP_647599.1, NP_004296.1, NP_647600.1, NP_647601.1).
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name BIN1 (BIN1 Antibody Abstract)
Background Synonyms: BIN1, bridging integrator 1, AMPH2, AMPHL, DKFZp547F068, MGC10367, SH3P9, amphiphysin II, amphiphysin-like, box dependant MYC interacting protein 1
Gene ID 274, 30948, 117028
NCBI Accession NP_647595, NP_647594, NP_647597, NP_647596, NP_647593, NP_004296, NP_647600, NP_647601, NP_647599, NP_647598
Research Area Cancer, Cell Cycle, Transcription Factors
Pathways
Application Notes ELISA: antibody detection limit dilution 1:1000.
Western blot: Experiments gave bands at approx 70 kDa and 60 kDa in Human Skeletal Muscle lysates after 0.1 µg/mL antibody staining. These bands correspond to earlier findings in literature with different antibodies (Chang et al, Cancer Res. 2007 Jan 1,67(1):100-7., PMID: 17210688). This protein has a calculated MW of 64.7 kDa according to NP_647593.1. Recommended concentration: 1-3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-BIN1 antibody (Bridging Integrator 1) (Internal Region) (ABIN334360) ABIN334360 (0.1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA ...
Background publications Ghaneie, Zemba-Palko, Itoh et al.: "Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival." in: Cancer biology & therapy, Vol. 6, Issue 2, pp. 192-4, 2007 (PubMed).

Catalog No. ABIN334360
$318.20
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