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Details for Product No. ABIN334360

Bridging Integrator 1 (BIN1) (Internal Region) antibody

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Antigen
Synonyms AMPH2, AMPHL, SH3P9, ALP-1, Amphl, BRAMP-2, bin1, MGC53185, amph2, amphl, sh3p9, MGC76187, cb57, zgc:86701, BIN1
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN334360
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-SDNAPAKGNKSPS, from the internal region of the protein sequence according to NP_004296.1, NP_647593.1, NP_647594.1, NP_647595.1, NP_647596.1, NP_647597.1, NP_647598.1, NP_647599.1, NP_647600.1, NP_647601.1.
Specificity This antibody is expected to recognise all ten reported isoforms (NP_647593.1, NP_647594.1, NP_647595.1, NP_647596.1, NP_647597.1, NP_647598.1, NP_647599.1, NP_004296.1, NP_647600.1, NP_647601.1).
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name BIN1
Background Synonyms: BIN1, bridging integrator 1, AMPH2, AMPHL, DKFZp547F068, MGC10367, SH3P9, amphiphysin II, amphiphysin-like, box dependant MYC interacting protein 1
Gene ID 274, 30948, 117028
NCBI Accession NP_004296.1, NP_647593.1, NP_647594.1, NP_647595.1, NP_647596.1, NP_647597.1, NP_647598.1, NP_647599.1, NP_647600.1, NP_647601.1
Research Area Cancer, Cell Cycle, Transcription Factors
Application Notes ELISA: antibody detection limit dilution 1:1000.
Western blot: Experiments gave bands at approx 70 kDa and 60 kDa in Human Skeletal Muscle lysates after 0.1 µg/mL antibody staining. These bands correspond to earlier findings in literature with different antibodies (Chang et al, Cancer Res. 2007 Jan 1,67(1):100-7., PMID: 17210688). This protein has a calculated MW of 64.7 kDa according to NP_647593.1. Recommended concentration: 1-3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Ghaneie, Zemba-Palko, Itoh et al.: "Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival." in: Cancer biology & therapy, Vol. 6, Issue 2, pp. 192-4, 2007 (PubMed).

Alternatives for antigen "Bridging Integrator 1 (BIN1)", type "Antibodies"
Hosts (31), (21), (4)
Reactivities (53), (37), (26), (14), (12), (4), (3)
Applications (43), (20), (12), (10), (8), (6), (3), (3), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (2), (2), (2), (1), (1), (1)
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