CACNA1F antibody

Catalog No. ABIN350143

Product Details anti-CACNA1F Antibody

Target: CACNA1F (Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1F antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for CACNA1F.

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from human CACNA1F conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for CACNA1F

Target: CACNA1F (Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F))

Alternative Name: CACNA1F (CACNA1F Products)

Background: Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Subcellular location: Membrane, Multi-pass membrane protein.,Alpha Subunit,Voltage-gated calcium channel subunit alpha Cav1.4, Voltage-dependent L-type calcium channel subunit alpha-1F

UniProt: O60840