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Details for Product No. ABIN350367

Hepcidin Antimicrobial Peptide (HAMP) (Prodomain) antibody

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Synonyms HEPC, HFE2B, LEAP1, PLTR, Hepc, Hamp1, Hepc1, hepcidin, Hepcidin, HAMP
»Alternatives Prodomain
»Alternatives Mouse (Murine)
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN350367
Quantity 500 µg
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from internal region of mouse Hepcidin (HAMP) conjugated to an immunogenic carrier protein has been used as the immunogen.
Isotype IgG
Specificity Appears to be specific for Hepcidin.
Purity IgG
Alternative Name Hepcidin (HAMP)
Background Function: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity.
Subcellular location: Secreted.
Tissue specificity: Highly expressed in the liver and to a much lesser extent in the heart. Also known as: Hepcidin, Liver-expressed antimicrobial peptide, LEAP-1, Putative liver tumor regressor, HAMP, HEPC, LEAP1.
UniProt Q9EQ21
Application Notes IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Pigeon, Ilyin, Courselaud et al.: "A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload." in: The Journal of biological chemistry, Vol. 276, Issue 11, pp. 7811-9, 2001 (PubMed).

Nicolas, Bennoun, Devaux et al.: "Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 15, pp. 8780-5, 2001 (PubMed).

Alternatives for antigen "Hepcidin Antimicrobial Peptide (HAMP)", type "Antibodies"
Hosts (43), (8), (6)
Reactivities (47), (12)
Applications (53), (39), (21), (11), (4), (4), (3), (2), (2), (2), (2), (2), (1)
Conjugates (4)
Epitopes (11), (9), (5), (3), (2), (2), (2), (2), (2), (2), (1), (1)