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Neuropeptide Y (NPY) (AA 20-70) antibody

Details for Product No. ABIN350526
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Antigen
Synonyms npya, pyy4, xnpy, MGC86288, prepronpy, PYY4, NPY02, RATNPY, RATNPY02, 0710005A05Rik, NPY, si:dkey-22m8.5, npy, npyb, preproNPY
Epitope
AA 20-70
(5), (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus), Rabbit, Xenopus laevis
(68), (35), (30), (13), (6), (1), (1), (1), (1), (1), (1)
Host
Goat
(63), (19), (4), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(51), (44), (28), (22), (15), (12), (11), (10), (3), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 500 µg
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Catalog No. ABIN350526
454.67 $
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Immunogen A synthetic peptide from aa region 20-70 of mouse NPY (Neuropeptide Y) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in many other species including human, rat, zebrafish and xenopus.
Isotype IgG
Specificity Specific for NPY.
Alternative Name NPY
Background Function: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Subcellular location: Secreted
Tissue specificity: One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. Also known as: Neuropeptide Y, Neuropeptide tyrosine, C-flanking peptide of NPY, CPON.
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Minth, Andrews, Dixon: "Characterization, sequence, and expression of the cloned human neuropeptide Y gene." in: The Journal of biological chemistry, Vol. 261, Issue 26, pp. 11974-9, 1986 (PubMed).

Minth, Bloom, Polak et al.: "Cloning, characterization, and DNA sequence of a human cDNA encoding neuropeptide tyrosine." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 81, Issue 14, pp. 4577-81, 1984 (PubMed).

Taylor, Wnek, Schroeder et al.: "Multiple obesity QTLs identified in an intercross between the NZO (New Zealand obese) and the SM (small) mouse strains." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 12, Issue 2, pp. 95-103, 2001 (PubMed).

Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

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