Secretory Carrier Membrane Protein 1 (SCAMP1) (Cytoplasmic Domain) antibody

Details for Product No. ABIN350821
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Antigen
Synonyms SCAMP, SCAMP37, AI415563, AW122395, 4930505M11Rik, zgc:77214, SCAMP1, scamp1, DKFZp459H1724
Epitope
Cytoplasmic Domain
(3), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Rat (Rattus)
(20), (14), (13), (1)
Host
Sheep
(22)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(22), (11), (4), (2), (1)
Pubmed 4 references available
Catalog no. ABIN350821
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the 1t cytoplasmic domain of human SCAMP1 (Secretory carrier associated membrane protein 1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and mouse.
Specificity Specific for TRPV6.
Purification IgG
Alternative Name SCAMP1 (Secretory carrier associated membrane protein 1)
Background Function: Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Widely expressed, with highest expression in brain. Also known as: SCAMP-1, SCAMP 1, Secretory carrier-associated membrane protein 1, Secretory carrier membrane protein 1, SCAMP 37.
UniProt Q9R186
Research Area Signaling, Metabolism
Application Notes A concentration of 10-50 µg/mL is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
General Brand, Castle: "SCAMP 37, a new marker within the general cell surface recycling system." in: The EMBO journal, Vol. 12, Issue 10, pp. 3753-61, 1993 (PubMed).

Singleton, Wu, Castle: "Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions." in: Journal of cell science, Vol. 110 ( Pt 17), pp. 2099-107, 1997 (PubMed).

Mao, Fu, Wu et al.: "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 14, pp. 8175-80, 1998 (PubMed).

Fernández-Chacón, Achiriloaie, Janz et al.: "SCAMP1 function in endocytosis." in: The Journal of biological chemistry, Vol. 275, Issue 17, pp. 12752-6, 2000 (PubMed).

Hosts (22)
Reactivities (20), (14), (13), (1)
Applications (22), (11), (4), (2), (1)
Epitopes (3), (3), (2), (1), (1), (1), (1), (1), (1)
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