Superoxide Dismutase 3, Extracellular (SOD3) (N-Term) antibody

Details for Product No. ABIN350844
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Synonyms SOD3, LOC780439, fb05f10, si:dkey-117m1.6, sod3, wu:fb05f10, EC-SOD, AI314465, ECSODPT, ECSOD, SODA.4
(19), (8), (6), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
(89), (41), (20)
(70), (39), (4), (1)
(10), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (IHC), Western Blotting (WB)
(97), (67), (56), (25), (17), (14), (10), (9), (8), (5), (4), (3), (2), (1)
Pubmed 5 references available
Quantity 500 μg
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Catalog No. ABIN350844
454.67 $
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Immunogen A synthetic peptide from the n-terminal region of human SOD3 conjugated to an immunogenic carrier protein was used as the immunogen.
Isotype IgG
Specificity Specific for SOD3.
Alternative Name SOD3
Background Function: Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Catalytic activity: 2 superoxide + 2 H(+) = O(2) + H(2)O(2).
Tissue specificity: Expressed in blood vessels, heart, lungs, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
Subcellular location: Secreted › extracellular space. Note: 99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium. Also known as: Superoxide dismutase 3, SODE, SOD E.
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Nozik-Grayck, Suliman, Piantadosi: "Extracellular superoxide dismutase." in: The international journal of biochemistry & cell biology, Vol. 37, Issue 12, pp. 2466-71, 2005 (PubMed).

Adachi, Morihara, Yamazaki et al.: "An arginine-213 to glycine mutation in human extracellular-superoxide dismutase reduces susceptibility to trypsin-like proteinases." in: Journal of biochemistry, Vol. 120, Issue 1, pp. 184-8, 1997 (PubMed).

Folz, Crapo: "Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD gene." in: Genomics, Vol. 22, Issue 1, pp. 162-71, 1994 (PubMed).

Hjalmarsson, Marklund, Engström et al.: "Isolation and sequence of complementary DNA encoding human extracellular superoxide dismutase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 18, pp. 6340-4, 1987 (PubMed).

Adachi, Ohta, Hayashi et al.: "The site of nonenzymic glycation of human extracellular-superoxide dismutase in vitro." in: Free radical biology & medicine, Vol. 13, Issue 3, pp. 205-10, 1992 (PubMed).

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