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Syntaxin 7 (STX7) antibody

Details for Product No. ABIN350943, Supplier: Log in to see
  • AI315064
  • AI317144
  • Aval
  • avl
  • Avl
  • AW107239
  • CG5081
  • DDBDRAFT_0187598
  • DDBDRAFT_0231537
  • DDB_0187598
  • DDB_0231537
  • Dmel\\CG5081
  • Dm Syx7
  • DmSyx7
  • dSyn7
  • F27G20.2
  • FCP-C
  • STX7
  • Syn7
  • Syntaxin-7
  • syntaxin-7
  • SYP24
  • Syx
  • syx7
  • SYX7
  • syx7/avl
Immunohistochemistry (IHC), Western Blotting (WB)
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Immunogen A synthetic peptide as a part of human Syntaxin-7 (STX7, Syn7, Syntaxin 7) conjugated to an immunogenic carrier protein was used as the immunogen.
Isotype IgG
Specificity Specific for Syntaxin-7.
Alternative Name Syntaxin 7 (STX7 Antibody Abstract)
Background Function: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.
Subunit: Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Interacts with VPS33A. Found in a complex with VAMP8 and VTI1B in the liver. Part of the SNARE core complex containing VAMP8, STX8 and VTI1B. Interacts with VPS11, VPS16 and VPS18.
Subcellular location: Early endosome membrane, Single-pass type IV membrane protein. Also known as: Syntaxin-7, STX7, Syn7.
Research Area Signaling
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Gevaert, Goethals, Martens, Van Damme, Staes, Thomas, Vandekerckhove: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003

Nakamura, Yamamoto, Wada, Futai: "Syntaxin 7 mediates endocytic trafficking to late endosomes." in: The Journal of biological chemistry, Vol. 275, Issue 9, pp. 6523-9, 2000

Prekeris, Yang, Oorschot, Klumperman, Scheller: "Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking." in: Molecular biology of the cell, Vol. 10, Issue 11, pp. 3891-908, 1999

Wang, Frelin, Pevsner: "Human syntaxin 7: a Pep12p/Vps6p homologue implicated in vesicle trafficking to lysosomes." in: Gene, Vol. 199, Issue 1-2, pp. 39-48, 1997