Trafficking Protein Particle Complex Subunit 1 (IC) (TPPC1) antibody

Details for Product No. ABIN351030, Supplier: Log in to see
Human, Mouse (Murine), Rat (Rattus)
Immunohistochemistry (IHC), Western Blotting (WB)
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Immunogen A synthetic peptide from human TPPC1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous with the corresponding sequence in mouse, rat and chicken.
Isotype IgG
Specificity Specific for TPPC1.
Alternative Name TPPC1
Background Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Subunit: Part of the multisubunit TRAPP (transport protein particle) complex.
Subcellular location: Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Also known as: Multiple myeloma protein 2, MUM-2, TRAPPC1, BET5, MUM2.
Research Area Signaling
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Gavin, Bösche, Krause, Grandi, Marzioch, Bauer, Schultz, Rick, Michon, Cruciat, Remor, Höfert, Schelder, Brajenovic, Ruffner, Merino, Klein, Hudak, Dickson, Rudi, Gnau, Bauch, Bastuck, Huhse et al.: "Functional organization of the yeast proteome by systematic analysis of protein complexes. ..." in: Nature, Vol. 415, Issue 6868, pp. 141-7, 2002 (PubMed).

Chiari, Foury, De Plaen, Baurain, Thonnard, Coulie: "Two antigens recognized by autologous cytolytic T lymphocytes on a melanoma result from a single point mutation in an essential housekeeping gene." in: Cancer research, Vol. 59, Issue 22, pp. 5785-92, 1999 (PubMed).

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