Xenopus TRPN1 (NompC, Putative Transient Receptor Potential Channel) antibody

Antigen: Xenopus TRPN1 (NompC, Putative Transient Receptor Potential Channel)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Xenopus laevis

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN351233

Additional Information

Alternative name: xenopusTRPN1 (nompC, Putative transient receptor potential channel)

UniProt: Q6RI86

Immunogen: A synthetic peptide as a part of xenopus TRPN1 (nompC, Putative transient receptor potential channel) conjugated to an immunogenic carrier protein was used as the immunogen.

Format: Lyophilized

Isotype: IgG

Description: FUNCTION: May function as an ion-channel regulator. May function with PKD2L1 as heteromeric taste channels. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in a subset of taste receptor cells distinct from those involved in bitter, sweet and umami taste. Expressed in circumvallate and foliate taste buds, but not in surrounding non-gustatory lingual epithelium cells. Expressed in testis. Also known as: Putative transient receptor potential channel, nompC.

Specificity: Appears to be specific for TRPN1.

Application Details

Application Notes: IHC, WB. Use at a concentration of 10-50 µg/ml. The optimal working concentration should be determined by the end user.

Purity: IgG

Storage: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Restrictions: For Research Use only

Publications

Shin, Adams, Paukert et al.: "Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 35, pp. 12572-7, 2005 (PubMed).