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Xenopus TRPN1 (NompC, Putative Transient Receptor Potential Channel) (AA 250-300) antibody

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AA 250-300
Xenopus laevis
Immunohistochemistry (IHC), Western Blotting (WB)
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Immunogen A synthetic peptide from aa region 250-300 of Xenopus TRPN1 conjugated to an immunogenic carrier protein was used as the antigen.
Isotype IgG
Specificity Specific for TRPN1.
Alternative Name TRPN1
Background Function: May function as an ion-channel regulator. May function with PKD2L1 as heteromeric taste channels.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in a subset of taste receptor cells distinct from those involved in bitter, sweet and umami taste. Expressed in circumvallate and foliate taste buds, but not in surrounding non-gustatory lingual epithelium cells. Expressed in testis. Also known as: Putative transient receptor potential channel, nompC.
Application Notes Use at a concentration of 10-50 µg/ml.
The optimal working concentration should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Shin, Adams, Paukert, Siba, Sidi, Levin, Gillespie, Gruender: "Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 35, pp. 12572-7, 2005 (PubMed).