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Details for Product No. ABIN351331

Vacuolar Protein Sorting 36 Homolog (S. Cerevisiae) (VPS36) (Internal Region) antibody

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C13orf9, EAP45, RGD1309754, Eap45, 1700010A24Rik, 2210415M20Rik, 2810408E15Rik, CG10711, Dmel\\CG10711, l(3)L5212, vps36, fj33d07, zgc:55965, wu:fj33d07, MUG13.23, MUG13_23, VPS36, DDBDRAFT_0205116, D ... show more
»Alternatives Internal Region
»Alternatives Mouse (Murine), Rat (Rattus)
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN351331
Quantity 500 µg
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the internal region of mouse Vacuolar protein-sorting-associated protein 36 (VPS36) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat.
Isotype IgG
Specificity Appears to be specific for VPS36.
Purity IgG
Alternative Name Vacuolar protein-sorting-associated protein 36 (VPS36)
Background Function: Component of the ESCRT-II complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery oftransmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL.
Subcellular location: Cytoplasm. Late endosome. Nucleus. NoteL Colocalizes with ubiquitinated proteins on late endosomes. Also known as: VPS36.
UniProt Q91XD6
Application Notes IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Kamura, Burian, Khalili et al.: "Cloning and characterization of ELL-associated proteins EAP45 and EAP20. a role for yeast EAP-like proteins in regulation of gene expression by glucose." in: The Journal of biological chemistry, Vol. 276, Issue 19, pp. 16528-33, 2001 (PubMed).

Gibbs, Weinstock, Metzker et al.: "Genome sequence of the Brown Norway rat yields insights into mammalian evolution." in: Nature, Vol. 428, Issue 6982, pp. 493-521, 2004 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

Alternatives for antigen "Vacuolar Protein Sorting 36 Homolog (S. Cerevisiae) (VPS36)", type "Antibodies"
Hosts (7), (1)
Reactivities (5), (4), (1)
Applications (8), (3), (2), (1), (1)
Epitopes (3), (2), (1)