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ZIC1-3 antibody (C-Term)

Zic1/2/3 Reactivity: Human IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN351417
  • Target
    ZIC1-3 (Zic1/2/3) (Zic Family Member 1/2/3 (Zic1/2/3))
    Binding Specificity
    C-Term
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    Specific for ZIC1, 2, 3.
    Cross-Reactivity
    Human, Mouse, Rat
    Cross-Reactivity (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogen
    A synthetic peptide from c-terminal region of human ZIC3 (Zinc finger protein ZIC 3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat and mouse.
    Isotype
    IgG
  • Application Notes
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handling Advice
    Avoid freeze and thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Expiry Date
    12 months
  • Target
    ZIC1-3 (Zic1/2/3) (Zic Family Member 1/2/3 (Zic1/2/3))
    Alternative Name
    ZIC1-3
    Background
    Function: Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation. Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1). HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs, including asplenia or polysplenia, symmetric liver, intestinal malrotation, and abnormal lung lobation.,Stem Cells,HTX, HTX1, Zic family member 3 (odd-paired Drosophila homolog heterotaxy 1), Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3), ZNF203
    UniProt
    O60481
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