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Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (Center) antibody

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Synonyms EHMT1, G9a, 9230102N17Rik, D330003E03, Eu-HMTase1, GLP, GLP1, KMT1D, mKIAA1876, EUHMTASE1, FP13812, bA188C12.1
(36), (28), (20), (19), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(115), (4), (3), (1)
(97), (17), (1)
(10), (10), (10), (10), (10), (5)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(100), (73), (10), (5), (4), (3), (3), (3)
Pubmed 2 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human EHMT1.
Isotype Ig
Specificity This antibody is specific to EHMT1 (Center).
Purification Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name EHMT1 (EHMT1 Antibody Abstract)
Background EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.Synonyms: EUHMTASE1, Eu-HMTase1, Euchromatic histone-lysine N-methyltransferase 1, G9a-like protein 1, GLP, GLP1, H3-K9-HMTase 5, Histone H3-K9 methyltransferase 5, Histone-lysine N-methyltransferase EHMT1, KIAA1876, KMT1D, Lysine N-methyltransferase 1D
Gene ID 79813, 9606
UniProt Q9H9B1
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (Center) antibody (ABIN356543) anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (Center) antibody
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Ogawa, Ishiguro, Gaubatz et al.: "A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells." in: Science (New York, N.Y.), Vol. 296, Issue 5570, pp. 1132-6, 2002 (PubMed).

Catalog No. ABIN356543
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