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Details for Product No. ABIN356723

PR Domain Containing 14 (PRDM14) (N-Term) antibody

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Antigen
Synonyms PFM11, PRDM14, prmd14, fc16b12, wu:fc16b12
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN356723
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PRDM14.
Specificity This antibody is specific to PRDM14 (PFM11) (N-term).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name PRDM14 / PFM11
Background Similar to acetylation and phosphorylation, histone methylation at the N terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET domain family, and another 17 make up the PR domain family that is related to the SET domain family. PRDM14 is part of a family of PR domain genes that are involved in tumorigenesis. It may function as a transcription factor.
Alternate names: PR domain zinc finger protein 14, PR domain-containing protein 14
Gene ID 63978
NCBI Accession 9606
UniProt Q9GZV8
Application Notes ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Jiang, Huang: "The yin-yang of PR-domain family genes in tumorigenesis." in: Histology and histopathology, Vol. 15, Issue 1, pp. 109-17, 2000 (PubMed).

Dias Neto, Correa, Verjovski-Almeida et al.: "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 7, pp. 3491-6, 2000 (PubMed).

Xiao, Wilson, Gamblin: "SET domains and histone methylation." in: Current opinion in structural biology, Vol. 13, Issue 6, pp. 699-705, 2003 (PubMed).

Alternatives for antigen "PR Domain Containing 14 (PRDM14)", type "Antibodies"
Hosts (10), (2), (2), (2)
Reactivities (14), (1), (1), (1), (1), (1), (1)
Applications (12), (8), (5), (3), (3), (2), (2)
Epitopes (4), (3), (2), (1), (1), (1), (1)
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