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Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) (C-Term) antibody

Details for Product No. ABIN356871, Supplier: Login to see
Antigen
  • id:ibd2914
  • nstm
  • wu:fb38a04
  • wu:fc55d07
  • zgc:123093
  • e2ig3
  • C77032
  • E2IG3
  • NNP47
  • NS
  • BC037996
  • Ns
Epitope
C-Term
28
17
8
6
6
6
6
4
4
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
83
41
16
1
1
Host
Rabbit
76
19
4
4
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
86
51
11
9
8
8
4
4
1
1
1
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human GNL3.
Isotype Ig
Specificity This antibody is specific to GNL3 (C-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Nucleostemin (E2IG3 Antibody Abstract)
Background GNL3 is found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle progression in stem cells and cancer cells, and may be required to maintain the proliferative capacity of stem cells.Synonyms: E2-induced gene 3 protein, E2IG3, GNL3, Guanine nucleotide-binding protein-like 3, NS, Novel nucleolar protein 47, Nucleolar GTP-binding protein 3
Gene ID 26354, 9606
UniProt Q9BVP2
Research Area Embryogenesis, Embryonic stem cells, Neural Stem Cell marker, Apoptosis/Necrosis
Pathways
Application Notes ELISA: 1/1,000. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) (C-Term) antibody (ABIN356871) anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) (C-Term) antibody
Background publications Ma, Pederson: "Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2630-5, 2007 (PubMed).