Acid Phosphatase, Prostate (ACPP) (C-Term) antibody

Details for Product No. ABIN359766
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Antigen
Synonyms ACPP, CD73, Nt5, 4921514H13Rik, AIRP, CN-IB, 5'-NT, ACP-3, ACP3, PAP, A030005E02Rik, FRAP, Lap, Ppal, Acpp11, RNACPP11, pap, acp-3, acp3, acpt, AMAP2, CENTB3, DDEF2, PAG3, Pap-alpha, SHAG1
Epitope
C-Term
(7), (4), (2), (2), (2), (2), (2), (2), (1), (1)
Reactivity
Human
(104), (25), (20), (13), (4), (1)
Host
Rabbit
(47), (43), (15), (6), (2), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(43), (42), (34), (25), (13), (12), (10), (6), (4), (2), (2), (2), (2), (2), (2), (2), (1)
Pubmed 3 references available
Quantity 0.4 mL
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Catalog No. ABIN359766
357.50 $
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ACPP.
Specificity This antibody reacts to ACPP.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name ACPP / Prostatic acid phosphatase
Background ACPP is an enzyme which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland.
Alternate names: ACP3, PAP, PSAP, Prostate acid phosphatase
Gene ID 55, 9606
UniProt P15309
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Johnson, Ellis, Noack et al.: "The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase." in: The Biochemical journal, Vol. 391, Issue Pt 3, pp. 699-710, 2005 (PubMed).

Klyushnenkova, Kouiavskaia, Kodak et al.: "Identification of HLA-DRB1*1501-restricted T-cell epitopes from human prostatic acid phosphatase." in: The Prostate, Vol. 67, Issue 10, pp. 1019-28, 2007 (PubMed).

Quintero, Araujo, Pulkka et al.: "Prostatic acid phosphatase is not a prostate specific target." in: Cancer research, Vol. 67, Issue 14, pp. 6549-54, 2007 (PubMed).

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