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ALDH1L1 antibody (Aldehyde Dehydrogenase 1 Family, Member L1) (AA 724-754)

Details for Product anti-ALDH1L1 Antibody No. ABIN360201, Supplier: Log in to see
Antigen
  • FDH
  • fthfd
  • ALDH1L1
  • FTHFD
  • DKFZp469C068
  • 10-FTHFDH
  • 10-fTHF
  • 1810048F20Rik
  • Fthfd
  • Neut2
Epitope
AA 724-754, C-Term
8
3
3
3
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
70
22
19
8
4
4
1
1
1
1
Host
Rabbit
53
24
Clonality
Polyclonal
Conjugate
This ALDH1L1 antibody is un-conjugated
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
51
25
23
23
22
15
9
4
3
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724~754 amino acids from the C-terminal region of Human ALDH1L1. Genename: ALDH1L1
Isotype Ig
Specificity This antibody recognizes ALDH1L1.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name ALDH1L1 / FTHFD (ALDH1L1 Antibody Abstract)
Background ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.Synonyms: 10-formyltetrahydrofolate dehydrogenase, Aldehyde dehydrogenase family 1 member L1
Gene ID 10840, 9606
UniProt O75891
Pathways
Application Notes ELISA: 1/1,000. Western blotting: 1/50-1/100. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-ALDH1L1 antibody (Aldehyde Dehydrogenase 1 Family, Member L1) (AA 724-754) (ABIN360201) anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) (AA 724-754), (C-Term) antibody
 image for anti-ALDH1L1 antibody (Aldehyde Dehydrogenase 1 Family, Member L1) (AA 724-754) (ABIN360201) anti-Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) (AA 724-754), (C-Term) antibody (Image 2)
Background publications Hosgood, Menashe, Shen et al.: "Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway." in: Carcinogenesis, Vol. 29, Issue 10, pp. 1938-43, 2008 (PubMed).

Lee, Lan, Kricker et al.: "One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia." in: Human genetics, Vol. 122, Issue 5, pp. 525-33, 2007 (PubMed).