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Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (Ser67) antibody

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Synonyms NNX3, RMP, gep, gna12, gna12l, AI414047, AI504261, Galpha12
(13), (13), (10), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1)
(51), (34), (30), (1), (1), (1), (1)
(52), (3)
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(33), (22), (14), (8)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S67 of human GNA12.
Isotype Ig
Specificity This antibody reacts to GNA12.
Purification Protein A column, followed by peptide affinity purification
Alternative Name G Protein Subunit alpha 12 / GNA12 (GNA12 Antibody Abstract)
Background Guanine nucleotide-binding proteins (G proteins) are modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 subunits, alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.Synonyms: G alpha-12, Guanine nucleotide-binding protein subunit alpha-12
Gene ID 2768, 9606
UniProt Q03113
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (Ser67) antibody (ABIN360476) anti-Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) (Ser67) antibody
Background publications Krakstad, Ardawatia, Aragay: "A role for Galpha12/Galpha13 in p120ctn regulation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 28, pp. 10314-9, 2004 (PubMed).

Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Scherer, Cheung, MacDonald et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, 2003 (PubMed).

Yamaguchi, Katoh, Negishi: "N-terminal short sequences of alpha subunits of the G12 family determine selective coupling to receptors." in: The Journal of biological chemistry, Vol. 278, Issue 17, pp. 14936-9, 2003 (PubMed).

Suzuki, Nakamura, Mano et al.: "Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 733-8, 2003 (PubMed).

Catalog No. ABIN360476
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