Complement Decay-Accelerating Factor (CD55) antibody

Details for Product No. ABIN371558
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Antigen
Synonyms Daf, Daf-GPI, Daf1, GPI-DAF, CR, CROM, DAF, TC, AI323748, Cd55b, Daf-TM, TM-DAF
Reactivity
Human
(188), (16), (6), (4), (3), (1), (1), (1)
Host
Mouse
(121), (72), (7), (3), (2), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(25), (23), (17), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
(123), (92), (48), (28), (23), (21), (20), (19), (10), (8), (4), (2), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

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Catalog No. ABIN371558
198.00 $
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Clone 143-30
Isotype IgG1
Characteristics Synonyms: Complement decay-accelerating factor
Purification Purified
Alternative Name CD55 / DAF
Background CD55, also known as decay accelerating factor (DAF), is a 64-73 kDa GPI-anchored singlechain glycoprotein that is expressed on all cells in contact with serum, including allhematopoietic cells and the vascular endothelium. A soluble form of CD55 is present inplasma and body fluids. CD55 is a member of the regulator of complement activity (RCA)family of proteins and is thought to play a role in the protection of cells from damage byautologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic inthe presence of phorbol esters. (Ref. 1-5)
UniProt P08174
Application Notes Flow Cytometry: < / = 1 µg/10e6 cells. Immunohistochemistry on Frozen Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer 100 mM Borate Buffered Saline, pH 8.2.No preservatives or amine-containing buffer salts added.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Holmes, Simpson, Wainwright et al.: "Preferential expression of the complement regulatory protein decay accelerating factor at the fetomaternal interface during human pregnancy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 8, pp. 3099-105, 1990 (PubMed).

Liszewski, Farries, Lublin et al.: "Control of the complement system." in: Advances in immunology, Vol. 61, pp. 201-83, 1996 (PubMed).

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