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CD55 antibody (Complement Decay-Accelerating Factor)

Details for Product anti-CD55 Antibody No. ABIN371558, Supplier: Login to see New
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Synonyms Daf, Daf-GPI, Daf1, GPI-DAF, CR, CROM, DAF, TC, AI323748, Cd55b, Daf-TM, TM-DAF
(296), (35), (7), (6), (5), (4), (3), (1)
(225), (89), (8), (7), (6), (4), (2)
Clonality (Clone)
Monoclonal ()
This CD55 antibody is un-conjugated
(49), (45), (25), (10), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
(230), (141), (63), (63), (43), (36), (34), (21), (11), (5), (5), (4), (3), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Clone 143-30
Isotype IgG1
Characteristics Synonyms: Complement decay-accelerating factor
Purification Purified
Alternative Name CD55 / DAF (CD55 Antibody Abstract)
Background CD55, also known as decay accelerating factor (DAF), is a 64-73 kDa GPI-anchored single chain glycoprotein that is expressed on all cells in contact with serum, including all hematopoietic cells and the vascular endothelium. A soluble form of CD55 is present in plasma and body fluids. CD55 is a member of the regulator of complement activity (RCA) family of proteins and is thought to play a role in the protection of cells from damage by autologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic in the presence of phorbol esters. (Ref.1-5)Synonyms: Complement decay-accelerating factor
UniProt P08174
Pathways Complement System
Application Notes Flow Cytometry: < / = 1 μg/10^6 cells. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Liszewski, Farries, Lublin et al.: "Control of the complement system." in: Advances in immunology, Vol. 61, pp. 201-83, 1996 (PubMed).

Holmes, Simpson, Wainwright et al.: "Preferential expression of the complement regulatory protein decay accelerating factor at the fetomaternal interface during human pregnancy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 8, pp. 3099-105, 1990 (PubMed).

Catalog No. ABIN371558
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