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HSPB8 antibody (C-Term)

HSPB8 Reactivity: Human WB, EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374275
  • Target See all HSPB8 Antibodies
    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
    Binding Specificity
    • 20
    • 15
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 91
    • 34
    • 21
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 67
    • 23
    • 1
    Goat
    Clonality
    • 64
    • 27
    Polyclonal
    Conjugate
    • 39
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSPB8 antibody is un-conjugated
    Application
    • 69
    • 35
    • 27
    • 27
    • 25
    • 13
    • 13
    • 12
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequence
    NELPQDSQEV TCT
    Specificity
    This antibody detects Heat shock protein beta-8 (HSPB8) at C-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    Immunogen
    Peptide from C Terminus of the protein sequence according to NP_055180.1 Genename: HSPB8
    Top Product
    Discover our top product HSPB8 Primary Antibody
  • Application Notes
    Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1 μg/mL. Approx 20-25 kDa band seen in human skeletal muscle lysate[Predicted MW of approx.25 kDa according to NP_055180].
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • Target
    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
    Alternative Name
    HSPB8 / HSP22 (HSPB8 Products)
    Background
    Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).Synonyms: Alpha-crystallin C chain, CRYAC, E2-induced gene 1 protein, E2IG1, Heat shock protein beta-8, Protein kinase H11, Small stress protein-like protein HSP22
    Gene ID
    26353
    NCBI Accession
    NP_055180
    UniProt
    Q9UJY1
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