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Pirin (PIR) (N-Term) antibody

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Synonyms 2310042L19Rik, Pirnl, zgc:92778, ATPIRIN1, PRN1, pirin, xpir
(14), (6), (5), (3), (2), (1), (1), (1)
Human, Mouse (Murine)
(47), (9), (7), (4), (3), (1), (1)
(18), (17), (10), (2)
(1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(43), (25), (8), (7), (4), (3), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide from the N Terminus of the protein sequence according to NP_003653.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Alternative Name Pirin / PIR (PIR Antibody Abstract)
Background The pirin gene encodes a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor, as well as B cell lymphoma 3-encoded oncoprotein, suggest that the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.Synonyms: 3-dioxygenase PIR, Probable quercetin 2, Probable quercetinase
Gene ID 8544
NCBI Accession NP_001018119
UniProt O00625
Application Notes Peptide ELISA: 1/128,000. Western Blot: 0.3-1.0 μg/mL. Detects a band of Approx 30-35 kDa in Human Heart lysate. (Predicted Molecular Weight: 32.5 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.
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Background publications Parada, Reis, Pinto et al.: "Chemopreventive Efficacy of Atorvastatin against Nitrosamine-Induced Rat Bladder Cancer: Antioxidant, Anti-Proliferative and Anti-Inflammatory Properties." in: International journal of molecular sciences, Vol. 13, Issue 7, pp. 8482-99, 2012 (PubMed).

Wendler, Kremmer, Förster et al.: "Identification of pirin, a novel highly conserved nuclear protein." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8482-9, 1997 (PubMed).

Catalog No. ABIN374451
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