Pirin (PIR) (N-Term) antibody

Details for Product No. ABIN374451
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Antigen
Synonyms 2310042L19Rik, Pirnl, zgc:92778, xpir, ATPIRIN1, PRN1, pirin
Epitope
N-Term
(5), (3), (2)
Reactivity
Human, Mouse (Murine)
(24), (4), (4), (2), (2), (1), (1)
Host
Goat
(11), (7), (6), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(22), (8), (4), (4), (3), (3), (3), (1), (1)
Pubmed 2 references available
Catalog no. ABIN374451
Quantity 0.1 mg
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide from the N Terminus of the protein sequence according to NP_003653.
Sequence GSSKKVTLSVLSREC
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Alternative Name Pirin / PIR
Background The pirin gene encodes a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor, as well as B cell lymphoma 3-encoded oncoprotein, suggest that the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.
Alternate names: 3-dioxygenase PIR, Probable quercetin 2, Probable quercetinase
Gene ID 8544
NCBI Accession NP_001018119.1
UniProt O00625
Application Notes Peptide ELISA: 1/128,000. Western Blot: 0.3-1.0 µg/ml. Detects a band of Approx 30-35kDa in Human Heart lysate. (Predicted Molecular Weight: 32.1kDa). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C.
Expiry Date 12 months
Supplier Images
anti-Pirin (PIR) (N-Term) antibody anti-Pirin (PIR) (N-Term) antibody
anti-Pirin (PIR) (N-Term) antibody (2) anti-Pirin (PIR) (N-Term) antibody (Image 2)
Background publications Wendler, Kremmer, Förster et al.: "Identification of pirin, a novel highly conserved nuclear protein." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8482-9, 1997 (PubMed).

Parada, Reis, Pinto et al.: "Chemopreventive Efficacy of Atorvastatin against Nitrosamine-Induced Rat Bladder Cancer: Antioxidant, Anti-Proliferative and Anti-Inflammatory Properties." in: International journal of molecular sciences, Vol. 13, Issue 7, pp. 8482-99, 2012 (PubMed).

Hosts (11), (7), (6), (1)
Reactivities (24), (4), (4), (2), (2), (1), (1)
Applications (22), (8), (4), (4), (3), (3), (3), (1), (1)
Epitopes (5), (3), (2)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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