Hermansky-Pudlak Syndrome 6 (HPS6) (Internal Region) antibody

Details for Product No. ABIN374513
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Synonyms RP11-302K17.1, 5330434M19Rik, BLOC2, ru, Hsp6
Internal Region
(1), (1), (1), (1)
Human, Mouse (Murine), Rat (Rattus)
(10), (3), (3)
(7), (3), (1)
Western Blotting (WB)
(9), (5), (3)
Pubmed 2 references available
Catalog no. ABIN374513
Quantity 0.1 mg
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Immunogen Peptide with sequence LRTELRDYRGLEC, from the internal region of the protein sequence
Specificity This antibody reacts to HPS6. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Porcine, Bovine.
Purification Affinity chromatography
Alternative Name HPS6
Background HPS6 has an intronless gene and may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. HPS6 interacts with Hermansky- Pudlak syndrome 5 protein. Mutations in HPS6 gene are associated with Hermansky- Pudlak syndrome type 6.
Alternate names: HPS-6, Hermansky-Pudlak syndrome 6 protein, Ru, Ruby-eye protein homolog
Gene ID 79803
NCBI Accession NP_079023.2
UniProt Q86YV9
Research Area Signaling
Application Notes Peptide ELISA: 1/32000. Western Blot: 1 - 3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Hermansky-Pudlak Syndrome 6 (HPS6) (Internal Region) antibody anti-Hermansky-Pudlak Syndrome 6 (HPS6) (Internal Region) antibody
Background publications Gautam, Chintala, Li et al.: "The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2)." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12935-42, 2004 (PubMed).

Smeazzetto, Schröder, Thiel et al.: "Phospholamban generates cation selective ion channels." in: Physical chemistry chemical physics : PCCP, Vol. 13, Issue 28, pp. 12935-9, 2011 (PubMed).

Hosts (7), (3), (1)
Reactivities (10), (3), (3)
Applications (9), (5), (3)
Epitopes (1), (1), (1), (1)
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