V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) (C-Term) antibody

Details for Product No. ABIN374642
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Antigen
Synonyms ERG, p55, erg-3, erg_E, D030036I24Rik, erg, erg_A, zgc:103429
Epitope
C-Term
(10), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(59), (17), (13), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Host
Goat
(33), (22), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1)
Application
Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(46), (21), (14), (13), (11), (5), (3), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN374642
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Immunogen Peptide with sequence C-PNTRLPTSHMPSH, from the C Terminus of the protein sequence
Specificity This antibody reacts to ERG.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name ERG
Background ERG (v-ets erythroblastosis virus E26 oncogene like isoform 2) is a transcriptional regulator. It may participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.Synonyms: Transcriptional regulator ERG, Transforming protein ERG
Gene ID 2078
NCBI Accession NP_001129626
UniProt P11308
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Hematopoietic Progenitors
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 μg/mL. Immunohistochemistry on paraffin sections: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, pH 7.3, 0.02 % sodium azide, 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
anti-V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) (C-Term) antibody anti-V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) (C-Term) antibody
Background publications Tomlins, Rhodes, Perner et al.: "Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer." in: Science (New York, N.Y.), Vol. 310, Issue 5748, pp. 644-8, 2005 (PubMed).

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