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Suppressor of Ty 16 (SUPT16) (Internal Region) antibody

Details for Product No. ABIN374777, Supplier: Login to see
Antigen
  • T12H20.3
  • T12H20_3
  • global transcription factor C
  • SPT16
  • Cdc68
  • Fact140
  • Spt16
  • Supt16h
Epitope
Internal Region
2
1
1
Reactivity
Human
11
7
Host
Goat
9
2
Clonality
Polyclonal
Application
Western Blotting (WB)
8
3
2
1
1
1
Supplier
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Immunogen Peptide with sequence C-DLTNKEGKKPEEK, from the internal region of the protein sequence
Specificity This antibody reacts to FACT / SUPT16H.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Porcine, Bovine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name SUPT16H / FACT140 (SUPT16 Antibody Abstract)
Background SUPT16H plays a role in general transcription, it has positive and negative effects on gene expression. Required for the appropriate synthesis during heat shock. Required for continued expression of cyclin genes that determine the passage through start during cell cycle control. it may act as an acidic activator. Its function is probably related to other spt genes.Synonyms: Chromatin-specific transcription elongation factor 140 kDa subunit, FACT 140 kDa subunit, FACT complex subunit SPT16, FACTp140, Facilitates chromatin transcription complex subunit SPT16
Gene ID 11198
NCBI Accession NP_009123
UniProt Q9Y5B9
Pathways
Application Notes Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Suppressor of Ty 16 (SUPT16) (Internal Region) antibody (ABIN374777) anti-Suppressor of Ty 16 (SUPT16) (Internal Region) antibody
Background publications Belotserkovskaya, Oh, Bondarenko et al.: "FACT facilitates transcription-dependent nucleosome alteration." in: Science (New York, N.Y.), Vol. 301, Issue 5636, pp. 1090-3, 2003 (PubMed).