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Details for Product No. ABIN374777

Suppressor of Ty 16 (SUPT16) (Internal Region) antibody

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Synonyms SPT16, T12H20.3, T12H20_3, global transcription factor C, Cdc68, Fact140, Spt16, Supt16h
»Alternatives Internal Region
»Alternatives Human
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN374777
Quantity 0.1 mg
346.50 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-DLTNKEGKKPEEK, from the internal region of the protein sequence
Specificity This antibody reacts to FACT / SUPT16H. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Porcine, Bovine.
Purification Affinity chromatography
Alternative Name SUPT16H / FACT140
Background SUPT16H plays a role in general transcription, it has positive and negative effects on gene expression. Required for the appropriate synthesis during heat shock. Required for continued expression of cyclin genes that determine the passage through start during cell cycle control. it may act as an acidic activator. Its function is probably related to other spt genes.
Alternate names: Chromatin-specific transcription elongation factor 140 kDa subunit, FACT 140 kDa subunit, FACT complex subunit SPT16, FACTp140, Facilitates chromatin transcription complex subunit SPT16
Gene ID 11198
NCBI Accession NP_009123.1
UniProt Q9Y5B9
Application Notes Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Belotserkovskaya, Oh, Bondarenko et al.: "FACT facilitates transcription-dependent nucleosome alteration." in: Science (New York, N.Y.), Vol. 301, Issue 5636, pp. 1090-3, 2003 (PubMed).

Alternatives for antigen "Suppressor of Ty 16 (SUPT16)", type "Antibodies"
Hosts (10), (6), (2)
Reactivities (18), (6), (1)
Applications (15), (8), (5), (4), (2), (2)
Conjugates (1)
Epitopes (6), (2), (1)