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Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase (MARCH6) (AA 701-712), (Internal Region) antibody

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Synonyms RGD1310927, RGD1565757, im:7161807, wu:fa98a02, si:dkey-40c17.2, Mar-06, 3830408G03, F830029L24Rik, mKIAA0597, DOA10, MARCH-VI, RNF176, TEB4
Internal Region, AA 701-712
(14), (12), (8), (7), (4), (3), (1), (1)
Human, Mouse (Murine)
(52), (19), (14), (1), (1), (1), (1), (1), (1), (1)
(33), (14), (6)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(36), (25), (11), (6), (2), (1)
Pubmed 2 references available
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Quantity 0.1 mg
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide with sequence from the internal region of the protein sequence according to NP_005876.2 Genename: MARCH6
Specificity This antibody recognizes TEB4 / MARCH-VI (701-712).
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Alternative Name MARCH6 / RNF176 (MARCH6 Antibody Abstract)
Background MARCH6 (Membrane associated RING finger protein 6) belongs to the MARCH family, which contains at least seven membrane associated RING-CH (MARCH)proteins. MARCH proteins are E3 ubiquitin ligases and are located to subcellular membranes.Synonyms: Doa10 homolog, E3 ubiquitin-protein ligase MARCH6, KIAA0597, MARCH-VI, Membrane-associated RING finger protein 6, Membrane-associated RING-CH protein VI, Protein TEB-4, RING finger protein 176, TEB-4, TEB4
Gene ID 10299, 9606
UniProt O60337
Application Notes Peptide ELISA: 1/16000. Western Blot: 0.2 - 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Image no. 1 for anti-Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase (MARCH6) (AA 701-712), (Internal Region) antibody (ABIN374941) anti-Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase (MARCH6) (AA 701-712), (Internal Region) antibody
Background publications Kreft, Wang, Hochstrasser: "Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)." in: The Journal of biological chemistry, Vol. 281, Issue 8, pp. 4646-53, 2006 (PubMed).

Buckley, Bonner, Brann: "Localization of a family of muscarinic receptor mRNAs in rat brain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 8, Issue 12, pp. 4646-52, 1989 (PubMed).

Catalog No. ABIN374941
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