Acylglycerol Kinase (AGK) (C-Term) antibody

Details for Product No. ABIN375166
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Antigen
Synonyms mulk, CATC5, CTRCT38, MTDPS10, MULK, 2610037M15Rik, 6720408I04Rik, AI465370, Mulk, RGD1562046, fi38e09, wu:fi38e09, zgc:55462
Epitope
C-Term
(6), (3), (2), (2)
Reactivity
Human
(29), (13), (13), (13), (13), (12), (12), (1), (1)
Host
Goat
(21), (6), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(19), (10), (5), (4), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN375166
368.50 $
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Immunogen Peptide with sequence CDPRKREQMLTSP, from the C Terminus of the protein sequence
Specificity This antibody reacts to Acylglycerol kinase.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name AGK / MULK
Background Acylglycerol Kinase is a lipid kinase whose function is to phosphorylate monoacylglycerol to form lysophosphatidic acid (LPA) and diacylglycerol to form phosphatidic acid (PA). It does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and of the downstream MAPK signaling pathway, thus leading to increased cell growth. It is overexpressed in prostate cancer, where it may play a role in initiation and progression. Two different isoform are known.Synonyms: Acylglycerol kinase, Multiple substrate lipid kinase
Gene ID 55750
NCBI Accession NP_060708
UniProt Q53H12
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
anti-Acylglycerol Kinase (AGK) (C-Term) antibody anti-Acylglycerol Kinase (AGK) (C-Term) antibody
Background publications Outeiro, Kontopoulos, Altmann et al.: "Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease." in: Science (New York, N.Y.), Vol. 317, Issue 5837, pp. 516-9, 2007 (PubMed).

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