Acylglycerol Kinase antibody (C-Term)

Catalog No. ABIN375166

Product Details anti-Acylglycerol Kinase Antibody

Target: Acylglycerol Kinase (AGK)

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Acylglycerol Kinase antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Acylglycerol kinase.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence CDPRKREQMLTSP, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Acylglycerol Kinase

Target: Acylglycerol Kinase (AGK)

Alternative Name: AGK / MULK (AGK Products)

Background: Acylglycerol Kinase is a lipid kinase whose function is to phosphorylate monoacylglycerol to form lysophosphatidic acid (LPA) and diacylglycerol to form phosphatidic acid (PA). It does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and of the downstream MAPK signaling pathway, thus leading to increased cell growth. It is overexpressed in prostate cancer, where it may play a role in initiation and progression. Two different isoform are known.Synonyms: Acylglycerol kinase, Multiple substrate lipid kinase

Gene ID: 55750

NCBI Accession: NP_060708

UniProt: Q53H12