Acylglycerol Kinase (AGK) (C-Term) antibody

Details for Product No. ABIN375166
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Antigen
Synonyms CATC5, CTRCT38, MTDPS10, MULK, Mulk, AI465370, 2610037M15Rik, 6720408I04Rik, RGD1562046, mulk, fi38e09, zgc:55462, wu:fi38e09
Epitope
C-Term
(4), (2), (2)
Reactivity
Human
(27), (12), (12), (12), (12), (12), (12)
Host
Goat
(22), (4), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(18), (10), (9), (5), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN375166
Quantity 0.1 mg
Price
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Immunogen Peptide with sequence CDPRKREQMLTSP, from the C Terminus of the protein sequence
Specificity This antibody reacts to Acylglycerol kinase. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse.
Purification Affinity chromatography
Alternative Name AGK / MULK
Background Acylglycerol Kinase is a lipid kinase whose function is to phosphorylate monoacylglycerol to form lysophosphatidic acid (LPA) and diacylglycerol to form phosphatidic acid (PA). It does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and of the downstream MAPK signaling pathway, thus leading to increased cell growth. It is overexpressed in prostate cancer, where it may play a role in initiation and progression. Two different isoform are known.
Alternate names: Acylglycerol kinase, Multiple substrate lipid kinase
Gene ID 55750
NCBI Accession NP_060708.1
UniProt Q53H12
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 - 3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Acylglycerol Kinase (AGK) (C-Term) antibody anti-Acylglycerol Kinase (AGK) (C-Term) antibody
Background publications Outeiro, Kontopoulos, Altmann et al.: "Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease." in: Science (New York, N.Y.), Vol. 317, Issue 5837, pp. 516-9, 2007 (PubMed).

Hosts (22), (4), (3)
Reactivities (27), (12), (12), (12), (12), (12), (12)
Applications (18), (10), (9), (5), (2), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (2)
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