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BNIP1 antibody (BCL2/adenovirus E1B 19kDa Interacting Protein 1) (Internal Region)

Details for Product anti-BNIP1 Antibody No. ABIN375177, Supplier: Login to see New
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Synonyms NIP1, SEC20, TRG-8, 2010005M06Rik, 5930429G21Rik, Sec20, 2900010M17Rik, AI853434, Apba2bp, Nip1, XB51
Internal Region, Isoform 1
(20), (17), (12), (11), (10), (4), (4), (4), (2), (2), (1), (1), (1), (1)
Human, Mouse (Murine), Rat (Rattus)
(111), (29), (26), (3), (1), (1), (1)
(75), (23), (15)
This BNIP1 antibody is un-conjugated
(6), (6), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(95), (52), (21), (11), (7), (4), (4), (1), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide with sequence C-DLLRQRKTTKESLAQ, from the internal region of the protein sequence
Specificity This antibody reacts to BNIP1. All reported variants represent isoform 1.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name BNIP1 (BNIP1 Antibody Abstract)
Background BNIPs belong to the proapoptotic BH3-only protein family. Three isoforms have been described so far. BNIP 1 is involved in the maintenance of ER-integrity. It is a member of the syntaxin 18 complex which is involved in membrane trafficking between the ER and Golgi. Four different BNIP 1 splice variants have been described so far, one of which contains a highly conserved BH3 domain. All BNIP 1 variants are able to interact with the apoptosis regulators BCL2 and BCL2L1.Synonyms: BCL2/adenovirus E1B 19 kDa protein-interacting protein 1, NIP1, SEC20L, TRG8, Transformation-related gene 8 protein, Vesicle transport protein SEC20
Gene ID 662
NCBI Accession NP_001196
UniProt Q12981
Research Area Signaling, Apoptosis/Necrosis
Application Notes Peptide ELISA: 1/8000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-BNIP1 antibody (BCL2/adenovirus E1B 19kDa Interacting Protein 1) (Internal Region) (ABIN375177) anti-BCL2/adenovirus E1B 19kDa Interacting Protein 1 (BNIP1) (Internal Region), (Isoform 1) antibody
Background publications Nakajima, Hirose, Taniguchi et al.: "Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion." in: The EMBO journal, Vol. 23, Issue 16, pp. 3216-26, 2004 (PubMed).

Catalog No. ABIN375177
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