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BNIP1 antibody (BCL2/adenovirus E1B 19kDa Interacting Protein 1) (Internal Region)

Details for Product anti-BNIP1 Antibody No. ABIN375177, Supplier: Login to see
Antigen
  • NIP1
  • SEC20
  • TRG-8
  • 2010005M06Rik
  • 5930429G21Rik
  • Sec20
  • 2900010M17Rik
  • AI853434
  • Apba2bp
  • Nip1
  • XB51
Epitope
Internal Region, Isoform 1
20
17
12
11
10
4
4
4
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
111
29
26
3
1
1
1
Host
Goat
75
23
15
Clonality
Polyclonal
Conjugate
This BNIP1 antibody is un-conjugated
6
6
6
5
5
5
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
95
52
21
11
7
4
4
1
1
1
Supplier
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Immunogen Peptide with sequence C-DLLRQRKTTKESLAQ, from the internal region of the protein sequence
Specificity This antibody reacts to BNIP1. All reported variants represent isoform 1.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name BNIP1 (BNIP1 Antibody Abstract)
Background BNIPs belong to the proapoptotic BH3-only protein family. Three isoforms have been described so far. BNIP 1 is involved in the maintenance of ER-integrity. It is a member of the syntaxin 18 complex which is involved in membrane trafficking between the ER and Golgi. Four different BNIP 1 splice variants have been described so far, one of which contains a highly conserved BH3 domain. All BNIP 1 variants are able to interact with the apoptosis regulators BCL2 and BCL2L1.Synonyms: BCL2/adenovirus E1B 19 kDa protein-interacting protein 1, NIP1, SEC20L, TRG8, Transformation-related gene 8 protein, Vesicle transport protein SEC20
Gene ID 662
NCBI Accession NP_001196
UniProt Q12981
Research Area Signaling, Apoptosis/Necrosis
Pathways
Application Notes Peptide ELISA: 1/8000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-BNIP1 antibody (BCL2/adenovirus E1B 19kDa Interacting Protein 1) (Internal Region) (ABIN375177) anti-BCL2/adenovirus E1B 19kDa Interacting Protein 1 (BNIP1) (Internal Region), (Isoform 1) antibody
Background publications Nakajima, Hirose, Taniguchi et al.: "Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion." in: The EMBO journal, Vol. 23, Issue 16, pp. 3216-26, 2004 (PubMed).