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Details for Product No. ABIN375207

Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (C-Term) antibody

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Synonyms Clp1, HIS1, CLP-1, 7330426E13Rik, Clp-1, fd44h02, hexim, wu:fd44h02, zgc:162976, CLP1, EDG1, MAQ1, HEXIM1
»Alternatives C-Term
»Alternatives Human
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN375207
Quantity 0.1 mg
346.50 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-HRQQERAPLSKFGD, from the C Terminus of the protein sequence
Specificity This antibody reacts to HEXIM1. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse.
Purification Affinity chromatography
Alternative Name HEXIM1
Background Positive transcription elongation factor b (P-TEFb) regulates eukaryotic gene expression at the level of elongation. HEXIM1 (or HEXIM2) forms a complex with p-TEFb and 7SK that leaves p-TEFb unable to activate transcriptional elongation.
Alternate names: CLP1, Cardiac lineage protein 1, EDG1, Estrogen down-regulated gene 1 protein, HIS1, Hexamethylene bis-acetamide-inducible protein 1, MAQ1, Menage a quatre protein 1
Gene ID 10614
NCBI Accession NP_006451.1
UniProt O94992
Research Area Cardiovascular, Hypertrophy, Cardiogenesis, Transcription Factors
Application Notes ELISA: 1/64000. Western Blot: 0.3 - 1µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Schulte, Czudnochowski, Barboric et al.: "Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24968-77, 2005 (PubMed).

Alternatives for antigen "Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1)", type "Antibodies"
Hosts (35), (11), (5)
Reactivities (49), (32), (25), (1), (1), (1)
Applications (38), (25), (11), (10), (9), (7), (4), (3), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1)