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Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (C-Term) antibody

Details for Product No. ABIN375207, Supplier: Login to see
Antigen
  • HEXIM1
  • fd44h02
  • hexim
  • wu:fd44h02
  • zgc:162976
  • CLP1
  • EDG1
  • HIS1
  • MAQ1
  • 7330426E13Rik
  • CLP-1
  • Clp1
  • Clp-1
Epitope
C-Term
17
17
15
14
10
8
7
6
5
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
113
49
33
3
1
1
1
1
1
Host
Goat
86
16
15
4
1
Clonality
Polyclonal
Conjugate
Un-conjugated
6
6
5
5
5
4
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
100
65
37
22
15
11
9
4
3
1
1
Supplier
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Immunogen Peptide with sequence C-HRQQERAPLSKFGD, from the C Terminus of the protein sequence
Specificity This antibody reacts to HEXIM1.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name HEXIM1 (HEXIM1 Antibody Abstract)
Background Positive transcription elongation factor b (P-TEFb) regulates eukaryotic gene expression at the level of elongation. HEXIM1 (or HEXIM2) forms a complex with p-TEFb and 7SK that leaves p-TEFb unable to activate transcriptional elongation.Synonyms: CLP1, Cardiac lineage protein 1, EDG1, Estrogen down-regulated gene 1 protein, HIS1, Hexamethylene bis-acetamide-inducible protein 1, MAQ1, Menage a quatre protein 1
Gene ID 10614
NCBI Accession NP_006451
UniProt O94992
Research Area Cardiovascular, Hypertrophy, Cardiogenesis, Transcription Factors
Pathways
Application Notes ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (C-Term) antibody (ABIN375207) anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (C-Term) antibody
Background publications Schulte, Czudnochowski, Barboric et al.: "Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24968-77, 2005 (PubMed).