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ATG7 Autophagy Related 7 Homolog (S. Cerevisiae) (ATG7) antibody

Details for Product No. ABIN387793, Supplier: Login to see
Antigen
  • AO090001000744
  • atg7
  • APG7-LIKE
  • APG7L
  • GSA7
  • 1810013K23Rik
  • Agp7
  • Apg7l
  • Atg7l
  • ATAPG7
  • ATATG7
  • ATG7
  • AUTOPHAGY 7
  • AUTOPHAGY-RELATED 7
  • K15I22.10
  • K15I22_10
Reactivity
Human
144
40
24
Host
Mouse
139
9
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
4
4
4
4
4
4
1
Application
Western Blotting (WB)
115
61
55
33
22
17
10
7
6
3
3
2
1
1
Supplier
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Immunogen Purified His-tagged APG7 protein was used to produced this monoclonal antibody.
Clone 29CT10-3-12
Isotype IgG2b kappa
Specificity Purified His-tagged APG7 protein was used to produced this monoclonal antibody.
Purification Ascites
Alternative Name ATG7 (ATG7 Antibody Abstract)
Background This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
Synonyms: APG7-LIKE, APG7L, DKFZp434N0735, GSA7, APG7 autophagy 7-like, autophagy-related protein 7, hAGP7, ubiquitin activating enzyme E1-like protein, ubiquitin-activating enzyme E1-like protein
Molecular Weight 77960 DA
Gene ID 10533
UniProt O95352
Research Area Cell Signaling, Cell Structure, Autophagy
Pathways
Application Notes WB = 1:500-2000
Restrictions For Research Use only
Format Liquid
Buffer Crude ascites with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ATG7 Autophagy Related 7 Homolog (S. Cerevisiae) (ATG7) antibody (ABIN387793) Western blot analysis of anti-APG7 Monoclonal Antibody (ABIN387793) by Recombinant AP...
Product cited in: Chiu, Kulp, Soni et al.: "Eradication of intracellular Salmonella enterica serovar Typhimurium with a small-molecule, host cell-directed agent." in: Antimicrobial agents and chemotherapy, Vol. 53, Issue 12, pp. 5236-44, 2009 (PubMed).

Background publications Metzger, Saukko, Van Che et al.: "Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7." in: Human genetics, Vol. 128, Issue 4, pp. 453-9, 2010 (PubMed).

Zhao, Yang, Liao et al.: "Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity." in: Nature cell biology, Vol. 12, Issue 7, pp. 665-75, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Xue, Chiu, Oleinick: "Atg7 deficiency increases resistance of MCF-7 human breast cancer cells to photodynamic therapy." in: Autophagy, Vol. 6, Issue 2, pp. 248-55, 2010 (PubMed).

Zhu, Dunner, McConkey: "Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells." in: Oncogene, Vol. 29, Issue 3, pp. 451-62, 2010 (PubMed).