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Details for Product No. ABIN388154

Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) (C-Term), (AA 458-487) antibody

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Antigen
Synonyms C77032, E2IG3, NNP47, NS, BC037996, Ns, e2ig3, wu:fc55d07, id:ibd2914, nstm, wu:fb38a04, zgc:123093
Epitope
»Alternatives C-Term, AA 458-487
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN388154
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This Nucleostemin (GNL3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 AA from the C-terminal region of human Nucleostemin (GNL3).
Clone RB13446
Isotype Ig
Specificity This GNL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465~495 amino acids from the C-term region of human GNL3.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Nucleostemin (GNL3)
Background GNL3 is found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle progression in stem cells and cancer cells, and may be required to maintain the proliferative capacity of stem cells.
Synonyms: Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, E2-induced gene 3 protein, Novel nucleolar protein 47, NNP47, E2IG3, NS
Molecular Weight 61997 DA
Gene ID 26354
UniProt Q9BVP2
Research Area Stem Cells, Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Ma, Pederson: "Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2630-5, 2007 (PubMed).

Alternatives for antigen "Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3)", type "Antibodies"
Hosts (36), (11), (3), (1)
Reactivities (46), (17), (12), (12), (12), (11)
Applications (40), (22), (9), (6), (4), (3), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
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