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Details for Product No. ABIN388453

Bone Morphogenetic Protein 3 (BMP3) (N-Term), (AA 8-36) antibody

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Antigen
Synonyms BMP-3A, PBMP3, 9130206H07, 9530029I04Rik, BMP-3, wu:fk96e01, BMP3, zgc:153939
Epitope
»Alternatives N-Term, AA 8-36
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN388453
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This Bmp3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 AA from the N-terminal region of human Bmp3.
Clone RB1855-1856
Isotype Ig
Specificity This Bmp3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~44 amino acids from the N-terminal region of human Bmp3.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Bmp3
Background The BMPs belong to the TGF-Beta superfamilyBMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
Molecular Weight 53406 DA
Gene ID 651
UniProt P12645
Research Area Cell Signaling, Cell Cycle, Neurology, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Dickinson, Kobrin, Silan et al.: "Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci." in: Genomics, Vol. 6, Issue 3, pp. 505-20, 1990 (PubMed).

Wozney, Rosen, Celeste et al.: "Novel regulators of bone formation: molecular clones and activities." in: Science (New York, N.Y.), Vol. 242, Issue 4885, pp. 1528-34, 1989 (PubMed).

Jin, Lu, Liong et al.: "Transcriptional mRNA of BMP-2, 3, 4 and 5 in trigeminal nerve, benign and malignant peripheral nerve sheath tumors." in: Histology and histopathology, Vol. 16, Issue 4, pp. 1013-9, 2001 (PubMed).

Alternatives for antigen "Bone Morphogenetic Protein 3 (BMP3)", type "Antibodies"
Hosts (48), (8), (3)
Reactivities (56), (20), (19), (12), (12), (12), (12)
Applications (41), (26), (11), (10), (7), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (5), (3), (3), (2), (1), (1), (1), (1), (1)
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