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Bone Morphogenetic Protein 4 (BMP4) (N-Term), (AA 5-34) antibody

Details for Product No. ABIN388454
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Antigen
Synonyms
bmp-4, zbmp-4, zgc:100779, XBMP-4, bmp2b, bmp2b1, bmp4, ofc11, xbmp4, zyme, BMP4, bmp-2, bmp2, bmp2-4, cb670, zbmp-2, zbmp2, ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, Bmp-4, Bmp2b, Bmp2b1, Bmp2b-1, BOMPR4A, ... show more
bmp-4, zbmp-4, zgc:100779, XBMP-4, bmp2b, bmp2b1, bmp4, ofc11, xbmp4, zyme, BMP4, bmp-2, bmp2, bmp2-4, cb670, zbmp-2, zbmp2, ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, Bmp-4, Bmp2b, Bmp2b1, Bmp2b-1, BOMPR4A, BMP-4 show less
Epitope
N-Term, AA 5-34
(12), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(103), (36), (31), (11), (8), (8), (4), (3), (3), (1)
Host
Rabbit
(106), (32), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(9), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(103), (70), (44), (30), (20), (15), (10), (5), (3), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 400 µL
Options
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Catalog No. ABIN388454
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This Bmp4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-34 AA from the N-terminal region of human Bmp4.
Clone RB01857
Isotype Ig
Specificity This Bmp4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12~42 amino acids from the N-terminal region of human Bmp4.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rabbit
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Bmp4
Background Bmp4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Molecular Weight 46555 DA
Gene ID 652
UniProt NP_001193
Research Area Cell Signaling, Cell Cycle, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Bone Morphogenetic Protein 4 (BMP4) (N-Term), (AA 5-34) antibody Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Bmp4 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Bone Morphogenetic Protein 4 (BMP4) (N-Term), (AA 5-34) antibody (2) Bmp4 Antibody (G20) (ABIN388454) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane).This demonstrates the Bmp4 antibody detected the Bmp4 protein (arrow).
anti-Bone Morphogenetic Protein 4 (BMP4) (N-Term), (AA 5-34) antibody (3) Western blot analysis of Bmp4 (arrow) using rabbit polyclonal Bmp4 Antibody (G20) (ABIN388454). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Bmp4 gene.
Background publications Chadwick, Wang, Li et al.: "Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells." in: Blood, Vol. 102, Issue 3, pp. 906-15, 2003 (PubMed).

Sorescu, Sykes, Weiss et al.: "Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response." in: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 31128-35, 2003 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN388454
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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