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Details for Product No. ABIN388454

Bone Morphogenetic Protein 4 (BMP4) (N-Term), (AA 5-34) antibody

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Antigen
Synonyms ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, Bmp-4, Bmp2b, Bmp2b1, Bmp2b-1, BOMPR4A, bmp-4, zbmp-4, zgc:100779, BMP-4, XBMP-4, bmp2b, bmp2b1, bmp4, ofc11, xbmp4, zyme, BMP4
Epitope
»Alternatives N-Term, AA 5-34
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN388454
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This Bmp4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-34 AA from the N-terminal region of human Bmp4.
Clone RB01857
Isotype Ig
Specificity This Bmp4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12~42 amino acids from the N-terminal region of human Bmp4.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rabbit
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Bmp4
Background Bmp4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Molecular Weight 46555 DA
Gene ID 652
UniProt NP_001193
Research Area Cell Signaling, Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Chadwick, Wang, Li et al.: "Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells." in: Blood, Vol. 102, Issue 3, pp. 906-15, 2003 (PubMed).

Sorescu, Sykes, Weiss et al.: "Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response." in: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 31128-35, 2003 (PubMed).

Alternatives for antigen "Bone Morphogenetic Protein 4 (BMP4)", type "Antibodies"
Hosts (93), (36), (4), (1)
Reactivities (102), (37), (32), (10), (8), (5), (5), (4), (4), (3), (1), (1)
Applications (102), (65), (44), (25), (15), (11), (10), (5), (4), (2), (1), (1), (1), (1)
Conjugates (13), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (4), (3), (3), (2), (1), (1), (1), (1), (1)
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