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Details for Product No. ABIN388613

YEATS Domain Containing 4 (N-Term), (AA 16-46) antibody

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Antigen
Synonyms
RGD1305741, zgc:100841, YAF9, GAS41, NUBI-1, 4930573H17Rik, B230215M10Rik, NuBI-1, MGC89432, YEATS4, CG9207, Dmel\\CG9207, dGas41, GB13136, GLIOMAS 41, K2N11.8, K2N11_8, TAF14B, TBP-ASSOCIATED FACTOR  ... show more
Epitope
»Alternatives N-Term, AA 16-46
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN388613
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This GAS41 (YEATS4/NuBI-1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 AA from the N-terminal region of human GAS41 (YEATS4/NuBI-1).
Clone RB8349
Isotype Ig
Specificity This GAS41 (YEATS4/NuBI-1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24~53 amino acids from the N-terminal region of human NuBI-1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name GAS41 (YEATS4/NuBI-1)
Background NuBI-1 is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. The gene for this protein has been shown to be amplified in tumors.
Synonyms: YEATS domain-containing protein 4, Glioma-amplified sequence-41, Gas41, NuMA binding protein 1, NuBI-1, NuBI1, YEATS4, GAS41,
Molecular Weight 26499 DA
Gene ID 8089
UniProt O95619
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Munnia, Schütz, Romeike et al.: "Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor." in: Oncogene, Vol. 20, Issue 35, pp. 4853-63, 2001 (PubMed).

Debernardi, Bassini, Jones et al.: "The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex." in: Blood, Vol. 99, Issue 1, pp. 275-81, 2001 (PubMed).

Zimmermann, Ahrens, Matthes et al.: "Targeted disruption of the GAS41 gene encoding a putative transcription factor indicates that GAS41 is essential for cell viability." in: The Journal of biological chemistry, Vol. 277, Issue 21, pp. 18626-31, 2002 (PubMed).

Lauffart, Gangisetty, Still: "Molecular cloning, genomic structure and interactions of the putative breast tumor suppressor TACC2." in: Genomics, Vol. 81, Issue 2, pp. 192-201, 2003 (PubMed).

Cai, Jin, Tomomori-Sato et al.: "Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 42733-6, 2003 (PubMed).

Alternatives for antigen "YEATS Domain Containing 4", type "Antibodies"
Hosts (45), (14), (1)
Reactivities (60), (29), (16), (14), (14), (2), (2), (1)
Applications (47), (22), (10), (5), (3), (3), (3), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (3), (2), (1), (1), (1), (1)
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