Ubiquitin Specific Peptidase 21 (USP21) (AA 226-256), (Center) antibody

Details for Product No. ABIN388783
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Antigen
Synonyms USP21, USP16, USP23, ESTM28, Usp16, Usp23, W53272
Epitope
AA 226-256, Center
(19), (9), (7), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(46), (3), (1), (1)
Host
Rabbit
(40), (5), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (4), (4), (4)
Application
Western Blotting (WB)
(41), (41), (19), (7)
Pubmed 2 references available
Quantity 400 μL
Options
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Catalog No. ABIN388783
291.50 $
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Immunogen This USP21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-256 AA from the Central region of human USP21.
Clone RB2871
Isotype Ig
Specificity This USP21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232~262 amino acids from the central region of human USP21.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name USP21
Background USP21 is a ubiquitin-specific protease, an enzyme that removes ubiquitin from ubiquitinated proteins. The encoded protein belongs to the C19 peptidase family, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. This protein has been reported to be capable of removing NEDD8 from NEDD8 conjugates.
Synonyms: Ubiquitin carboxyl-terminal hydrolase 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, Deubiquitinating enzyme 21, NEDD8-specific protease, USP21, USP23,
Molecular Weight 62656 DA
Gene ID 27005
UniProt Q9UK80
Research Area Stem Cells, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Ubiquitin Specific Peptidase 21 (USP21) (AA 226-256), (Center) antibody Western blot analysis of hUSP21-L241 (ABIN388783) in NCI-H460 cell line lysates (35 µg/lane). USP21 (arrow) was detected using the purified polyclonal antibody.
Background publications Gong, Kamitani, Millas et al.: "Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins." in: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14212-6, 2000 (PubMed).

Puente, Sánchez, Overall et al.: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, 2003 (PubMed).

Validation Images
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