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Details for Product No. ABIN388814

Growth Differentiation Factor 11 (GDF11) (N-Term), (AA 32-61) antibody

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Antigen
Synonyms BMP11, BMP-11, Bmp11, GDF11
Epitope
»Alternatives N-Term, AA 32-61
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN388814
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 AA from the N-terminal region of human GDF11.
Clone RB01875-01876
Isotype Ig
Specificity This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40~69 amino acids from the N-terminal region of human GDF11.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name GDF11
Background GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
Synonyms: Growth/differentiation factor 11 [Precursor], GDF-11, Bone morphogenetic protein 11, GDF11, BMP11
Molecular Weight 45090 DA
Gene ID 10220
UniProt O95390
Research Area Stem Cells, Cell Signaling, Neurology, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Gamer, Wolfman, Celeste et al.: "A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos." in: Developmental biology, Vol. 208, Issue 1, pp. 222-32, 1999 (PubMed).

Lee, McPherron: "Myostatin and the control of skeletal muscle mass." in: Current opinion in genetics & development, Vol. 9, Issue 5, pp. 604-7, 1999 (PubMed).

Alternatives for antigen "Growth Differentiation Factor 11 (GDF11)", type "Antibodies"
Hosts (18), (7)
Reactivities (25), (11), (11), (11), (11)
Applications (12), (12), (9), (5), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (3), (1), (1)
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