Serine Palmitoyltransferase (AA 531-562), (C-Term) antibody

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AA 531-562, C-Term
Human, Mouse (Murine)
Clonality (Clone)
Polyclonal ()
Western Blotting (WB)
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Immunogen This Serine Palmitoyltransferase (SPTLC2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-562 AA from the C-terminal region of human Serine Palmitoyltransferase (SPTLC2).
Clone RB4729
Isotype Ig
Specificity This SPTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from 532-562 human SPTLC2.
Predicted Reactivity Hamster
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Serine Palmitoyltransferase (SPTLC2)
Background Serine palmitoyltransferase (SPT) is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.
Synonyms: Serine palmitoyltransferase 2, Long chain base biosynthesis protein 2, LCB 2, Serine-palmitoyl-CoA transferase 2, SPT 2, SPT2
Molecular Weight 62924 DA
Gene ID 9517
NCBI Accession NP_004854
Research Area Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Serine Palmitoyltransferase (AA 531-562), (C-Term) antibody (ABIN389107) The anti-SPTLC2 Pab (ABIN389107) is used in Western blot to detect SPTLC2 in mouse li...
Background publications Weiss, Stoffel: "Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis." in: European journal of biochemistry / FEBS, Vol. 249, Issue 1, pp. 239-47, 1997 (PubMed).

Hillier, Lennon, Becker, Bonaldo, Chiapelli, Chissoe, Dietrich, DuBuque, Favello, Gish, Hawkins, Hultman, Kucaba, Lacy, Le, Le, Mardis, Moore, Morris, Parsons, Prange, Rifkin, Rohlfing, Schellenberg et al.: "Generation and analysis of 280,000 human expressed sequence tags. ..." in: Genome research, Vol. 6, Issue 9, pp. 807-28, 1997 (PubMed).

Takeda, Yano, Eng, Zeng, Bell: "A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones." in: Human molecular genetics, Vol. 2, Issue 11, pp. 1793-8, 1994 (PubMed).