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Details for Product No. ABIN389107

Serine Palmitoyltransferase (SPTLC2) (C-Term), (AA 531-562) antibody

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Antigen
Epitope
C-Term, AA 531-562
Reactivity
Human, Mouse (Murine)
Host
Rabbit
Clonality (Clone) Polyclonal ()
Application
Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN389107
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This Serine Palmitoyltransferase (SPTLC2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-562 AA from the C-terminal region of human Serine Palmitoyltransferase (SPTLC2).
Clone RB4729
Isotype Ig
Specificity This SPTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from 532-562 human SPTLC2.
Predicted Reactivity Hamster
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Background Serine palmitoyltransferase (SPT) is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.
Synonyms: Serine palmitoyltransferase 2, Long chain base biosynthesis protein 2, LCB 2, Serine-palmitoyl-CoA transferase 2, SPT 2, SPT2
Molecular Weight 62924 DA
Gene ID 9517
UniProt NP_004854
Research Area Protein Modifications, Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Takeda, Yano, Eng et al.: "A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones." in: Human molecular genetics, Vol. 2, Issue 11, pp. 1793-8, 1994 (PubMed).

Hillier, Lennon, Becker et al.: "Generation and analysis of 280,000 human expressed sequence tags." in: Genome research, Vol. 6, Issue 9, pp. 807-28, 1997 (PubMed).

Weiss, Stoffel: "Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis." in: European journal of biochemistry / FEBS, Vol. 249, Issue 1, pp. 239-47, 1997 (PubMed).

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